Huldah Sang

Huldah Sang

Research Assistant Professor

Ph.D., Pathobiology, Kansas State University, USA
M.Sc., Molecular Life Sciences, Wageningen University, The Netherlands
B.Sc., Biological Sciences, Moi University, Kenya

K-233 Mosier Hall
785-532-5997
Email
Main campus email

Research

Research focuses on developing innovative live-vectored vaccine strategies targeting both veterinary and human pathogens. Primary efforts center on advancing a recombinant Bovine Parainfluenza Virus type 3 platform for delivery of subunit vaccines against Bovine Viral Diarrhea Virus, African Swine Fever Virus, Highly Pathogenic Avian Influenza, and Plasmodium falciparum, alongside the development of antibody-based biotherapeutics.

  1. Sang H, Kim T, Kumar R, McCall J, Abraham A, Koynarski T, Zajac M, Abdelsalam KW, Hernandez Muguiro D, Bauer K, Plattner BL, Mwangi W. Novel BPI3Vc-vectored chimeric BVDV antigens elicit broadly neutralizing antibodies in cattle. Front Immunol. 2026. 17:1711852.

  2. Kumar R, Kim T, Zajac MD, Libanori-Artiaga B, Sang H, Sangewar N, Heitmann E, Deepak K, McCall J, Burton L, Olson S, Adetunji S, Richt JA, Hammer SE, Trujillo JD, Mwangi W. Live-vectored antigen cocktail confers protection against African swine fever virus (ASFV) Georgia 2007/1 challenge. NPJ Vaccines. 2026 Feb 12;11. PMID: 41680174.

  3. Sang H, Kim T, Kumar R, McCall J, Abraham A, Koynarski T, Zajac M, Abdelsalam KW, Hernandez Muguiro D, Bauer K, Plattner BL, Mwangi W. Novel BPI3Vc-vectored surface displayed fusion and hemagglutinin-neuraminidase antigens elicit broadly neutralizing antibodies in cattle. Front Immunol. 2026;16:1702440.17024. PMID: 41766820.

  4. Altman PX, Ozorowski G, Stanfield RL, Haakenson J, Appel M, Parren M, Lee WH, Sang H, Woehl J, Saye-Francisco K, Sewall LM, Joyce C, Song G, Porter K, Landais E, Andrabi R, Wilson IA, Ward AB, Mwangi W, Smider VV, Burton DR, Sok D. Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire. PLoS Pathog. 2024 Sep;20(9):e1012042. PMID: 39250525.

  5. Huang R, Warner Jenkins G, Kim Y, Stanfield RL, Singh A, Martinez-Yamout M, Kroon GJ, Torres JL, Jackson AM, Kelley A, Shaabani N, Zeng B, Bacica M, Chen W, Warner C, Radoicic J, Joh J, Dinali Perera K, Sang H, Kim T, Yao J, Zhao F, Sok D, Burton DR, Allen J, Harriman W, Mwangi W, Chung D, Teijaro JR, Ward AB, Dyson HJ, Wright PE, Wilson IA, Chang KO, McGregor D, Smider VV. The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2. Proc Natl Acad Sci U S A. 2023 Sep 26;120(39):e2303455120. PMID: 37722054.