Core Facilities

AMP Core

The AMP Core provides personalized, project-specific support and expertise to facilitate the use of animal models and pathological services. Existing infrastructure includes a new laser capture microdissection instrument. The AMP Core will also produce hybridomas and hyper-immune sera for the development of diagnostic tests essential to COBRE research projects.

Analytical Chemistry Core

The Analytical Chemistry laboratory is housed in Mosier Hall, Room P221 of the College of Veterinary Medicine complex. This core laboratory is equipped with state of the art analytical instrumentation, including UPLC, ICP-MS, GC-MS/MS and ion chromatography.

Biomedical Core Facilities

The new collaborative research facility represents a critical component of the university's research infrastructure to support biomedical and biomanufacturing studies and direct support of K-State's Center on Emerging and Zoonotic Infectious Diseases. The newly constructed, core-facility suite will assemble state of the art technologies in a single location to facilitate the delivery of coordinatred services for academic, corporate and federal researchers, providing a complete range of services from whole tissues to single-cell nucleic acid analyses.

Confocal Core

Originally founded in 2002 through an NIH-COBRE, the Confocal Core offers researchers a choice of three laser scanning confocal microscopes including LSM 700, 800 and 880 Airyscan to support all manner of imaging needs. Techniques supported include multi-channel imaging, quantitative analysis, colocalization, FRET, FRAP, 3D reconstruction, microfluorometry and super-res on both live and fixed cells. Provisions are available for live cell perfusion experiments. The facility also includes access to tissue-sectioning equipment to include a cryostat and Vibratome.

Flow Cytometry Core

Offers cytometer capabilities to perform polychromatic analysis via the four-laser/14-detector capabilities. The facility also provides access to cell sorter resources for up to three lasers and an assortment of filters and detectors to quickly sort a variety of cells either chilled or at physiologic temperature into a multitude of culture receptacles for further processing.

Analytical chemistry by UPC/MS/MS

Molecular and Cellular Biology (MCB) Core

The MBC Core provides technological support and significant research equipment/resources to all biomedical researchers at K-State and within the Regional Scientific Network. In addition, the MCB Core Laboratory offers training to faculty, staff, postdocs, graduate, and undergraduate students on the use of MCB Core equipment and technologies.

Nanotechnology Core

The Nanotechnology Core facility in the Department of Anatomy and Physiology in the KSU College of Veterinary Medicine (CVM) is a multiuser facility serving CVM, KSU campus, and research and commercial institutes outside campus. A well-equipped tissue culture facility can provide service for multiple investigators. A dedicated microscopic imaging room if available and includes bright field, dark field, and fluorescence microscopy. The core has two plate readers capable of absorbance, fluorescence, and luminescence based assays. The range of molecular biological instrumentation includes a QuantStudio 7 Flex, a Luminex 200, and a Chirascan CD spectrophotometer, allowing the core lab to be used for RT-PCR, ELISA, chemokine and cytokine assays, and thermodynamic and 3D structural characterization of proteins. State-of-the-art nanoparticle characterization equipment, such as Zetasizer, Nanosight, and a CPS high resolution disk centrifuge are available for measuring size and concentration of nanoparticles in suspension. A fully equipped surgical suite for small animals (up to 100 lb.) and an IVIS bio-imaging system facilitate in vivo experiments.

Since 2013, the Next-Generation Sequencing (NGS) Core Lab at the K-State College of Veterinary Medicine has provided short and long-read sequencing services using Illumina, Nanopore, and PacBio (2020) platform technologies. Whole genome sequencing, RNA-seq, metagenomic sequencing, amplicon sequencing, bacterial and viral sequencing, and the supporting bioinformatics analyses are among the services offered by the NGS Core Lab.