Rachel Palinski
Assistant Professor
Director of Next-generation Sequencing
Ph.D. Kansas State University
B.S. University of Georgia
156 CVM East/ KSUIC, Research Park
Phone:785-532-5709
Email: rpalinski@vet.k-state.edu
Service
My service interests focus on developing effective tools for detecting and characterizing novel and emerging viruses. Next-Generation Sequencing (NGS) is the predominant technology used in this lab which allows us to characterize viral populations and detect potential pathogens without prior sequencing knowledge. We have identified several novel viruses from either cell culture isolates or directly from clinical samples. A few of our previous findings include porcine parainfluenza virus 1, posaviruses and porcine circovirus 3. Our techniques are applied to samples taken from outbreak situations in which all suspected pathogens have tested negative as well as samples taken from healthy animals for microbiome analysis.
Research
My primary research interests include understanding the ecological factors that drive viral evolution. Livestock epidemic patterns may be associated with environmental, evolutionary and management factors. I seek to determine the relative balance of specific factors by which an outbreak occurs. My previous research involved dissecting the molecular ecology of swine vesicular diseases including Foot-and-Mouth Disease Virus and Vesicular Stomatitis Virus. By understanding the drivers of viral evolution, we can mitigate the effects of epidemics on livestock producers. My future interests include implementing risk assessments on individual farm management, environment and microbial populations to provide guidelines to maximize production by mitigating disease.
Additionally, my other research interests involve follow-up studies from NGS analyses, particularly for new or uncommon viruses. The purpose of this research is to determine the association of the particular microbe to disease. These studies may involve epidemiologic, pathological or pathogenesis investigations.
Publications
Palinski RM, Sangula A, Gakuya F, Bertram MR, Pauszek SJ, Hartwig EJ, Smoliga GS, Obanda V, Omondi G, VanderWaal K, Arzt J. Foot-and-mouth disease virus serotype A Genome Sequence from Kenya in 2016. 2019. MRA. 10.1128/MRA.00987-19.
Palinski RM, Sangula A, Gakuya F, Bertram MR, Pauszek SJ, Hartwig EJ, Smoliga GS, Obanda V, Omondi G, VanderWaal K, Arzt J. First report of Near-Complete Genome Sequences of Foot-and-Mouth Disease Viruse Serotype O strains from Kenya. 2019. MRA. 10.1128/MRA.00808-19.
Palinski RM, Sangula A, Gakuya F, Bertram MR, Pauszek SJ, Hartwig EJ, Smoliga GS, Obanda V, Omondi G, VanderWaal K, Arzt J. Genome Sequences of Foot-and-Mouth Disease Virus SAT1 and SAT2 strains from Kenya in 2014 to 2016. 2019. MRA. 10.1128/MRA.00809-19.
Bertram MR, Palinski RM, Ranjan R, Biswal JK, Pauszek SJ, Hartwig EJ, Smoliga GS, Fish IH, Subramaniam S, Mohapatra JK, Das B, Pattnaik B, Arzt J. Genome sequences of 18 Foot-and-Mouth Disease Virus Outbreak Strains of Serotype O Sublineage In2001d from India 2013 to 2014. 2019. MRA. 10.1128/MRA.00776-19.
Fish IH, Vierra D, Ehizibolo D, Palinski R, Bertram M, Pauszek SJ, Hartwig EJ, Smoliga GS, Arzt J. Near-Full-Length Genome Sequence of a Foot-and-Mouth Disease Virus of Serotype Southern African Territories 2 Isolated from Nigeria in 2014. 2019. MRA. 10.1128/MRA.00788-19.
Chai C, Palinski R, Xu Y, Wang Q, Cao S, Geng Y, Zhao Q, Wen Y, Huang X, Yan Q, Ma X, Wen X, Huang Y, Han X, Ma W, Wu R. Aerosol and Contact Transmission Following Intranasal Infection of Mice with Japanese Encephalitis Virus. 2019. Viruses. 10.3390/v11010087.
Arzt J, Bertram MR, Vu LT, Pauszek SJ, Hartwig EJ, Smoliga GR, Palinski R, Stenfeldt C, Fish IH, Hoang BH, Phuong NT, Hung VV, Vu PP, Dung NK, Dong PV, Tien NN, Dung DH. First Detection and Genome Sequence of Senecavirus A in Vietnam. 2019. MRA. 10.1128/MRA.01247-18.
Palinski RM, Bertram MR, Vu LT, Pauszek SJ, Hartwig EJ, Smoliga GR, Stenfeldt C, Fish IH, Hoang BH, Phuong NT, Hung VV, Vu PP, Dung NK, Dong PV, Tien NN, Tho ND, Dung DH, Arzt J. First Genome Sequence of Foot-and-Mouth Disease Virus Serotype O Sublineage Ind2001e from Southern Vietnam. 2019. MRA. 10.1128/MRA.01424-18.
Stenfeldt C, Hartwig EJ, Smoliga GR, Palinski R, Silva EB, Bertram MR, Fish IH, Pauszek SJ, Arzt J. Contact Challenge of Cattle with Foot-and-Mouth Disease Virus Validates the Role of the Nasopharyngeal Epithelium as the Site of Primary and Persistent Infection. 2018. mSphere. 10.1128/msphere.00493-18.
Palinski RM, Piñeyro P, Shang P, Yuan F, Guo R, Fang Y, Byers E, Hause BM. A novel porcine circovirus distantly related to known circoviruses is associated with porcine dermatitis and nephropathy syndrome and reproductive failure. 2016. J Virol. JVI-01879-16.
Hause BM, Palinski RM, Hesse R, Anderson G. Highly diverse posaviruses in swine feces are aquatic in origin. 2016. J. Gen. Virol. JGV.0.000461.
Palinski RM, Mitra N, Hause BM. Discovery of a novel Parvovirinae virus, porcine parvovirus 7, by metagenomic sequencing of porcine rectal swabs. 2016. Virus Genes. 10.1007/s11262-016- 1322-1.
Palinski RM, Chen Z, Henningson JN, Lang Y, Rowland RR, Fang Y, Prickett J, Gauger PC, Hause BM. Widespread detection and characterization of porcine parainfluenza 1 in pigs in the United States. 2015. J. Gen. Virol. JGVV.0.000343.