Pathobiology Group Graduate Faculty
Anderson, G.A. - Professor, DVM, PhD
Apley, Michael - DVM, PhD, ACVCP Diplomate
Blecha, Frank - Professor, MS, PhD
Dr. Blecha's long range research interests focus on the interrelationship of immunology and physiology in domestic food animals. His current research topics include: Evaluation of the regulatory mechanisms involved in innate immunity and in stress- and pathogen-induced immune alterations, cytokine immunopotentiation and regulation, and investigations of the influence of environmental stressors on cellular and antibody mediated immune responses in domestic animals.
Chang, K.O. - Assistant Professor, DVM, PhD
Chengappa, M.M. - Professor, DVM, MVSc, MS, PhD, Diplomate ACVM
Dr. Chengappa's research interests include the pathogenesis of bacterial diseases, specifically diseases caused by Pasteurella spp., Streptococcus suis, Fusobacterium necrophorum and Actinomyces pyogenes in food animals. He is attempting to identify and characterize important virulence factors and/or protective antigens of these organisms. In addition, he is studying the incidence of toxin-producing E. coli in greyhounds with or without diarrhea to assess the role of such E. coli in acute diarrhea cases.
Chowdhury, Shafiqul - Professor, DVM, MS, PhD
Bovine herpesvirus type 1 (BHV-1) causes respiratory infections and occasionally abortions in cattle. BHV-5 (Bovine encephalitis herpesvirus) causes neurological disease in calves. These two viruses continue to be the major cause of yearly losses to the cattle industry. Dr. Chowdhury's research interests are to study the role of virus glycoproteins in their differential pathogenesis of disease and to develop suitable recombinant vaccines. He has established that glycoproteins (g) gC, gD and gE of these two viruses are significantly differences when their nucleotide sequences are compared. Currently, gene-deleted and gene-exchanged BHV-1 and BHV-5 recombinant viruses involving these three glycoproteins are being constructed in his laboratory. He has developed a rabbit model in which he can differentiate BHV-1 and BHV-5 infection based on their neuro-pathogenic properties.
DeBey, Brad. - Associate Professor, DVM, PhD, ACVP Diplomate
Dritz, Steve, DVM, PhD
Dryden, Michael - Professor, DVM, PhD
Dr. Dryden's primary research focus relates to investigations of the epidemiology and control of fleas infesting dogs, cats and human dwellings, focusing on development of non-traditional control strategies, the false perception of the necessity for premise application of neurotoxic insecticides and development of resistance to these compounds. In addition, his other areas of research concern investigations of environmental contamination and transmission and control of helminth parasites and the interactions and potential transmission of parasites between urban wildlife, humans and their pets.
Ganta, Roman, MS, PhD
Kastner, Justin - Assistant Professor, PhD
Dr. Kastner serves as Assistant professor of food safety and security in the Department of Diagnostic Medicine/Pathobiology, Justin Kastner conducts scholarly activities related to trade policy, the history of science, economic history, and multidisciplinary research and writing. Dr. Kastner publishes and lectures on an array of issues: the World Trade Organization (WTO), the WTO Agreement on the Application of Sanitary and Phytosanitary Measures, veterinary history, the history of public health, U.S.-Canadian border issues, and the history of trade disputes regarding food safety and animal disease. In addition to conducting multidisciplinary research, Dr. Kastner routinely authors commentaries for the press. Co-director of the website for Food Safety and Security at Kansas State University, Dr. Kastner has worked with teams to create multimedia information products (e.g., online videos and FLASH-based research tools). Dr. Kastner also coordinates Frontier—an interdisciplinary program for the historical studies of border security, food safety, and trade policy.
Keeton, Kerry S. - DVM, PhD, ACVP Diplomate
Larson, Robert - DVM, PhD, ACT, ACVPM Diplomate
Ma, Wenjun - PhD, Justus-Liebig-University, Giessen, Germany
Moro, Manuel, DVM, MS, PhD
Mosier, Derek - Professor, DVM, PhD, Diplomate ACVM
The focus of his laboratory is the study of infectious diseases of cattle. Major investigations in his laboratory involve the pathogenesis and immunity to bovine pneumonic pasteurellosis and bovine cryptosporidiosis. Objectives of these studies are to increase our understanding of the mechanisms of virulence of Pasteurella haemolytica, P. multocida, and Cryptosproidium parvum, and the host response to these organisms. Identification of protective antigens and investigation of efficacious methods to administer identified antigens is a major goal of his studies.
Nagaraja, T. G. - Professor, BVSc, MVSc, PhD
Dr. Nagaraja's research interests include studies of anaerobic bacteria and protozoa of the rumen in relation to ruminal function and disorders, and the microbiology of the gastrointestinal tract of animals in relation to health and disease.
Narayanan, Sanjeev - Assistant Professor, DVM, PhD, Diplomate ACVM
Nguyen, Annelise Thu - Assistant Professor, DVM, PhD
Nietfeld, Jerome - Associate Professor, DVM, MS, PhD, Diplomate ACVP
His primary research involves enteric diseases of food animal, especially the diagnosis and prevention of Salmonella and enterotoxigenic Escherichia coli. He is involved in collaborative projects to study the effects of various dietary constituents and management practices on the carriage and shedding of Salmonella enterica serotype Typhimurium by pigs. His lab is responsible for testing E. coli isolates from pigs for known virulence colonization factors and enterotoxins, and for PCR testing for Mycoplasma species, Ureaplasma diversum, and Chlamydophila and Chlamydia species.
Oberst, Richard - Associate Professor, DVM, PhD
Dr. Oberst's research interest focus on development of automated, user-friendly protocols for the application of genetic diagnosis of infectious agents of veterinary importance that utilizes advanced polymerase chain reaction protocols. His goal is to demonstrate DNA-based technology for utilization is diagnostic veterinary medical, environmental and food safety procedures with rapid, specific, and sensitive detection procedures that reduce costs and increase through-put on clinical and environmental diagnostic samples covering a wide range of disease agents.
Oehme, Frederick - Professor, DVM, MS, PhD, Diplomate ABVT and ABT, Fellow ATS
Dr. Oehme's research focus on investigations of the biochemical actions and effects of toxicants in response to clinical problems that pose questions demanding laboratory investigations. The studies are applicable to toxic hazards in man and domestic animals, and a variety of experimental animals and model systems are used to document the biochemical-pathophysiological changes. Novel patient management and treatment procedures for intoxicated individuals are also evaluated in his laboratory.
Payne, Patricia A. - DVM, PhD
Pickrell, John - Associate Professor, DVM, PhD, Diplomate ABT
Dr. Pickrell has research interests in environmental toxicology-the development-therapy of chronic, allergic, toxic cardiopulmonary injury, the characterization and remediation of toxic dusts and adsorbed gases in agricultural confinement systems, and enhancing learning by using test-, videotape- and CD-ROM- based real-life problem solving.
Phebus, Randy, MS, PhD
Renter, David - Assistant Professor, DVM, PhD
Dr. Renter's research involves the application of epidemiologic principles and methods to the study of disease agents associated with livestock and food products. His focus is on livestock health and food safety with a primary emphasis on beef cattle. He studies both pre- and post-harvest food safety issues, bacterial pathogens, antimicrobial use/resistance, and chemical residues. His livestock health research has emphasized the use of clinical, diagnostic, and demographic data for establishing the health status of populations. Additional research interests include: development and application of methods for diagnostic test validation and estimation of disease burden; combining molecular and epidemiologic data for determining the epidemiology of infectious diseases; and combining multiple data sources for determining the health status of populations.
Takemoto, Dolores J. - Professor of Biochemistry
My laboratory is studying the role of protein kinase C isoforms in control of gap junctions and in repair during diabetes. Diabetes results in a loss of protein kinase C gamma from both lens and retina, resulting in changes in gap junction control. This contributes to damage seen during diabetic cataract and retinopathy. My laboratory is also studying the role of food antioxidants which contribute to protection from cancer and from damage during diabetes.
Weiss, Mark, PhD - Associate Professor Neuroscience
Our research is focused on two areas. First, we are interested in the function and location of neural circuits that control blood pressure and body fluid homeostasis. To elucidate these circuits, we use a variety of neuroscience techniques including electrophysiology, transneuronal transport of alpha-herpesviruses, and activity dependent regulation of gene expression in the nervous system. Second, we are interested in the fate of non-embryonic stem cells following transplantation. We are using a novel population of stem cells derived from the umbilical cord matrix (UCM), also known as Wharton's Jelly, for this work. We are examining the therapeutic potential and the safety of UCM cells in animal models of neurodegenerative disease.
Wilkerson, Melinda - Assistant Professor, DVM, PhD, Diplomate ACVP
Dr. Wilkerson's principal research interests is comparative immunopathology or immunologic/pathologic mechanisms of disease in domestic animals. Recent research involves dissection of the cytokine response generated in goats with chronic arthritis induced by lentivirus, Caprine Arthritis Encephalitis (CAEV). Similar to Rheumatoid Arthritis, CAEV induced arthritis is a disease perpetuated by the consequences of the inflammatory products released in the joint. Therefore, her goal is to understand the mechanisms involved in joint destruction so that appropriate therapeutic modalities can be implemented. This project includes investigation of the role of a retrovirus in the induction of arthritis. Additional research interests include implementation of flow cytometry techniques to measure lymphoblastogenesis, cell cycle analysis, apoptosis, and respiratory burst function in neutrophils. She also, has expertise in immunohistochemical techniques to define leukocyte subpopulations in diseased tissues from domestic animals.
Wisely, Samantha - Assistant Professor, PhD
Wyatt, Carol, MS, PhD
Zurek, Ludek - Assistant Professor, PhD
Adjunct Graduate Faculty
Ackleson, Jason - PhD - Adjunct, University of New Mexico, Las Cruces, NM
Kelly Lechtenberg - DVM, Ph. D - Adjunct, Midwest Veterinary Services, Inc., Oakland, NE
Sargeant, Janice M. - DVM, MS, PhD, Adjunct, McMaster University, Ontario, Canada.
Stewart, George C. - Ph. D., Adjunct, University of Missouri, Columbia, MO.
Tucker, Mark D. - PhD, Adjunct, Sandia National Labs, Las Alamos, NM.