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College of Veterinary Medicine

Jürgen A. Richt

 Regents Distinguished Professor & KBA Eminent Scholar

DVM (1985), University of München, Germany
PhD Virology (1988), University of Giessen, Germany

Kansas State University, Manhattan, KS
Regents Distinguished Professor, Diagnostic Medicine Pathobiology
Office: Mosier Hall K-224-B
Phone: (785) 532 -2793 
Fax: (785) 532 3373
Email: jricht@vet.k-state.edu

Research

The overall goal of my research is to investigate emerging diseases of livestock focusing mainly on viral and prion diseases.  We work on influenza viruses, especially swine and avian influenza viruses.  We try to understand molecular mechanisms of how influenza viruses are transmitted between animal species and which viral genes are critical for this process. In addition, we try to develop broader and more efficient vaccines. Reverse genetics technology is one of the techniques used in this line of research.  Rift Valley Fever virus is another zoonotic pathogen we are working on. Our goal is the development of novel vaccines and diagnostic tools. The prion research conducted is based on prion protein-deficient knock-out cattle, which we previously generated. Here we try to produce knock-in cattle expressing mutated bovine prion proteins using homologous recombination.  Recently, I became the director of the Center of Excellence for Emerging and Zoonotic Animal Diseases (CEEZAD), funded by the Department of Homeland Security.

Selected Publications

Ma W, Lager KM, Li X, Janke BH, Mosier DA, Painter LE, Ulery ES, Ma J, Lekcharoensuk P, Webby RJ, Richt JA. 2011.Pathogenicity of swine influenza viruses possessing an avian or swine-origin PB2 polymerase gene evaluated in mouse and pig models. Virology. 85: 1214-1223

Ma W., Oberst R., Li X, Clouser D, Hesse R, Rowland R, Richt JA. 2010. Rapid detection of the pandemic 2009 H1N1 virus M gene by real-time and gel-based RT-PCR assays. Influenza Other Respi Viruses. 4:397-403.

Ma, W., and Richt, J.A. 2010. Swine influenza vaccines: current status and future perspectives. Anim Health Res Rev. 11: 81-96

Ma W, Lager KM, Lekcharoensuk P, Ulery ES, Janke BH, Solorzano A, Webby RJ, Garcia-Sastre A, Richt JA. 2010. Viral reassortment and transmission after coinfection of pigs with classical H1N1 and triple reassortant H3N2 swine influenza viruses. J. Gen. Virol.  91: 2314-2321

Ma, W, Kahn, RE, Richt, JA. 2009. The Pig as a Mixing Vessel for Influenza Viruses: Human and Veterinary Implications. J. Mol. Gen. 3: 158-166

Weingartl HM, Albrecht RA, Lager KM, Babiuk S, Marszal P, Neufeld J, Embury-Hyatt C, Lekcharoensuk P, Tumpey TM, García-Sastre A, Richt JA. 2009. Experimental infection of pigs with the human 1918 pandemic influenza virus. J Virol. 83:4287-96

Richt JA, Feldmann H. 2009. Emerging zoonoses: recent advances and future challenges. Zoonoses Public Health. 56:257

Ferguson-Smith MA, Richt JA. 2009. Rare BSE mutation raises concerns over risks to public health. Nature. 457:1079

Hamir AN, Kunkle RA, Greenlee JJ, Richt JA. 2009. Experimental oral transmission of United States origin scrapie to neonatal sheep. J Vet Diagn Invest. 21:64-68

Richt JAHall SM. (2008). BSE case associated with prion protein gene mutation. PLoS Pathog. 4:e1000156