Derek A. Mosier
Department Head Interim
DVM 1978, Kansas St. U.
PhD 1985, Oklahoma St. U.
Diplomate 1986, American College of Vet Pathologists
I participate in the General and Systemic Pathology courses presented during the second year of the veterinary curriculum. Teaching involves lectures, laboratories, case-based discussions, and computer-assisted multimedia presentations.
Our laboratory conducts research on bovine infectious diseases. Specific projects include investigation of virulence factors and immunogens of Mannheimia haemolytica and P. multocida and the host response to infection by these organisms.
I participate in the residency training program in veterinary anatomic pathology
Uhlich GA, McNamara P, Iandolo JJ, Mosier DA: Cloning and characterization of the gene encoding Pasteurella haemolytica FnrP, a regulator of the Escherichia colisilent hemolysin SheA. J Bacteriol, 181:3845-3848, 1999.
Uhlich GA, McNamara P, Iandolo JJ, Mosier DA: FnrP interactions with the Pasteurella haemolyticaleukotoxin promoter. FEMS Microbiol. Letters, 186: 73-77, 2000.
Chapes, S.K., Mosier D.A., Wright, A.D., Hart, M.L.: MHCII, Tlr4, Nramp1 Genes Control Host Pulmonary Resistance Against the Opportunistic Bacterium Pasteurella pneumotropica. J. Leukocyte Biol., 69:381-386, 2001.
Hart, M.L., Mosier D.A., Chapes, S.K.: Toll-Like receptor 4-positive macrophages protect mice from Pasteurella pneumotropica-induced pneumonia. Infect. Immun. 71:663-670, 2003.
Armbrust L.J., Mosier D.A., Nelson E.L., Hart M.L., Chapes S.K.: Comparison of pulmonary computed tomography and pathologic findings in mice infected with Pasteurella-induced pneumonia. Am. J. Vet. Res. 66:835-838, 2004.
Hollis, L.C., Smith, J.F., Johnson, B.J., Kapil, S., Mosier D.A.: A comparison of serological responses when modified-live infectious bovine rhinotracheitis virus vaccine and Mannheimia haemolytica bacterin-toxoid are administered with needle-free versus conventional needle-based injection in yearling feedlot steers. Bov. Pract. 39:106-109, 2005.
Rogers, D.P., Wyatt, C.R., Walz, P.H., Drouillard, J.S., Mosier D.A.: Bovine alveolar macrophage neurokinin-1 and response to substance P. Vet. Immunol. Immunopathol. 112:290-295, 2006.
Linde, A., Mosier D.A., Blecha, F., Melgarejo, T: Innate immunity and inflammation: New frontiers in comparative cardiovascular pathology. Cardiovasc. Res. 73:26-36, 2007.