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College of Veterinary Medicine

Frederick W. Oehme: 1933-2018

Emeritus Professor of Toxicology, Pathobiology, Medicine and Physiology

BS 1957, Cornell U.
DVM 1958, Cornell U. 
MS 1962, Kansas St. U.
Dr Med Vet 1964, Justus Liebig U.
Diplomate 1968, American Board of Vet. Toxicology
PhD 1969, U. of Missouri
Diplomate 1980, American Board of Toxicology
Diplomate 1982, Acad. of Toxicological Sciences


Biochemical actions of toxicants, utilizing comparative medicine as a research and diagnostic tool in toxicology, identifying the effects of environmental chemicals on public health, and furthering new information development in clinical and diagnostic veterinary and human toxicology. More than 875 scientific contributions as professional publication, including 3 books and many book chapters and presented over 730 presentations on national and international professional and scientific platforms.


Instruction in clinical and diagnostic toxicology to 3rd and 4th year students in the professional curriculum. Mentored more than 55 residents and MS or PhD students to successfully complete training programs in toxicology.


Clinical services program of diagnostic testing, patient care and information responses for toxicology assistance providing diagnostic toxicology laboratory service, clinical consultation on patient and forensic toxicology, and providing information services in response to professional and public requests. Served on study sections of various NIH Institutes and scientific advisory panels for the Environmental Protection Agency, the Food and Drug Administration, the National Research Council and the World Health Organization International Program on Chemical Safety. Editor, The International Journal Veterinary and Human Toxicology and on the editorial boards of numerous other scientific journals. Charter member and fellow of the American Academy of Clinical Toxicology, the American Academy of Veterinary and Comparative Toxicology, and the Academy of Toxicological Sciences. Served as past–president of the Society of Toxicology, the American Academy of Clinical Toxicology and the Worlds Federation of Clinical Toxicology and Poison Control Centers.

Selected Publications

FW Oehme, JA Pickrell. 2003. Genetically Engineered Corn Rootworm Resistance: Potential for Reduction of Human Health Effects from Pesticides. Biochemical and Environmental Sciences 16: 17-28.

MR Bruins, S Kapil, FW Oehme. 2003. Characterization of a Small Plasmid (pMBCP) from Bovine Pseudomonas pickettii that Confers Cadmium Resistance. Ecotoxicol Environ Safety 54:241-248.

RR Dalefield, FW Oehme, GR Krieger. 2001. Principles of Risk Assessment. In: Clinical Environmental Health and Toxic Exposures, 2nd Ed, JB Sullivan Jr, GR Krieger, Eds. Lippincott Williams & Wilkins, Philadelphia, PA: 77-92.

Dalefield RR, Oehme F W, Milliken GA. 2001. Cholinesterase Activity: Muscarinic Receptor Ratios in Canine and Feline Brains. Veterinary and Human Toxicology 43: 19-21.

Oehme F W. 2001. Profiles in Toxicology: The Society of Toxicology’s 1977 Actions on Laboratory Accreditation, Professional Certification, and Good Laboratory Practices in Toxicology. Toxicological Sciences 62: 187-190.

Oehme F W, Mannala S. 2001. Pesticide use in Veterinary Medicine. In Handbook of Pesticide Toxicology, Second Edition, Vol. One, Krieger R, Editor. Academic Press, San Diego, CA: 263-274.

Dalefield RR, Oehme F W, Krieger GR. 2001. Principles of Risk Assessment. In Clinical Environmental Health and Toxic Exposures, Second Edition, Sullivan Jr JB, Krieger GR, Editors. Lippincott Williams and Wilkins, Philadelphia, PA: 77-92.

Bruins MR, Kapil S, Oehme F W. 2000. Pseudomonas picketti: A Common Soil and Groundwater Aerobic Bacteria with Pathogenic and Biodegradation Properties. Ecotoxicology and Environmental Safety 47: 105-111.

Cathers TE, Isaza R, Oehme F W. 2000. Acute Ibuprofen Toxicosis in a Ferret. JAVMA. 216:1426-1428.

Bruins MR, Kapil S, Oehme F W. 2000. Microbial Resistance to Metals in the Environment. Ecotoxicology and Environmental Safety 45:198-207.

Oehme F W, Rumbeiha WK. 1999. Veterinary Toxicology. In General and Applied Toxicology, Second Edition, Volume 3, Ballantyne B, Marrs T, Syversen T, Editors. Macmillan Reference Ltd, London: 1509-1526.

Oehme F W, Pickrell JA. 1999. An Analysis of the Chronic Oral Toxicity of Polyehter Ionophore Antibiotics in Animals. Veterinary and Human Toxicology 41:251-257.

Dalefield RR, Oehme F W. 1999. The Presence of a Muscarinic Receptor on Canine Erythrocyte Membranes. General Pharmacology 32:341-344.

Dalefield RR, Oehme F W. 1999. Cholinesterase Activity: Muscarinic Receptor Ratios in Canine and Feline Brains. Toxicological Sciences 48(1-S):99.

Oehme F W, Dalefield RR. 1999. The Presence of a Muscarinic Receptor on Canine Erythrocyte Membranes. Toxicological Sciences 48(1-S):37-38.

Basaraba RJ, Oehme F W, Vorhies MW, Stokka GL. 1999. Toxicosis in Cattle from Concurrent Feeding of Monensin and Dried Distiller’s Grians Contaminated with Macrolide Antibiotics. J. Vet. Diagn. Invest. 11:67-74.

Dalefield RR, Oehme F W. 1998. Detection of Metabolites of a Veterinary Counter-Irritant in Canine Urine. Veterinary and Human Toxicology. 40:231-233.

Dalefield RR, Oehme F W. 1997. Stability of Water Nitrate Levels During Prolonged Boiling. Veterinary and Human Toxicology. 39:313.

Smith E A, Prues S L, Oehme F W. 1997. Environmental Degradation of Polyacrylamides. II. Effects of Environmental (Outdoor) Exposure. Ecotoxicology and Environmental Safety. 37:76-91.

Rumbeiha W K, Oehme F W. 1997. Fumonisin Exposure to Kansans Through Consumption of Corn-Based Market Foods. Vet. and Human Toxicology. 39:220-225.

Abou-Donia M B, Wilmarth K R, Abdel-Rahman A A, Jensen K F, Oehme F W, Kurt T L. 1996. Increased Neurotoxicity Following Concurrent Exposure to Pyridostigmine .Bromide, DEET, and Chlorpyrifos. Fundamental and Applied Toxicology. 34:201-222.

Smith E A, Prues S L, Oehme F W. 1996. Environmental Degradation of Polyacrylamides. 1. Effects of Artificial Environmental Conditions: Temperature, Light and pH . Ecotoxicology and Environmental Safety. 35:1121-135.

Oehme F W, Coppock R W, Mostrom M S, Khan A A. 1996. A Review of the Toxicology of Air Pollutants: Toxicology of Chemical Mixtures. Veterinary and Human Toxicology 38:371-377.

Abou-Donia M B, Wilmarth K R, Jensen K F, Oehme F W, Kurt T L. 1996. Neurotoxicity Resulting From Co-exposure to Pyridostigmine Bromide, DEET, and Permethrin: Implications of Gulf War Chemical Exposures, Journ Toxicol Environ Health 48: 35-56.

Rumbeiha W K, Lin Y-S, Oehme F W. 1995 Comparison of N-Acetylcysteine and Methylene Blue, Alone or in Combination, for Treatment of Acetaminophen Toxicosis in Cats. Am J Vet Res 56:1529-1533.

Abdel-Mageed A B, Welti R, Oehme F W, Pickrell J A. 1994. Perinatal Hypocuprosis Affects Synthesis and Composition of Neonatal Lung Collagen, Elastin and Surfactant. Amer Journ Physiol 267 (Lung Cell Mol Physiol 11):L679-L685.

Barrett D S, Oehme F W, Kruckenberg S M, Smith J E. 1994. Clinical Manifestations and Leukocyte Neurotoxic Esterase and Red Blood Cell and Plasma Acetylcholinesterase Activities in Swine Following a Single Oral Dose of Tri-O- Cresyl Phosphate. Vet Human Toxicol 36:103-109.

Barett D S, Oehme F W. 1994. The Effects of a Single Oral Dose of Tri-O-Cresyl Phosphate on Neurotoxic Esterase and Acetylcholinesterase Activities in the Central Nervous System. Erythrocytes and Plasma. Vet Human Toxicol 36:1-4.

Abdel-Mageed A B, Oehme F W. 1991. The Effects of Various Dietary Zinc Concentrations on the Biological Interactions of Zinc, Copper and Iron in Rats. Biological Trace Elements Res 29:239-256.

Oehme F W, Williams and Wilkins. 1988. Textbook of Large Animal Surgery, 2nd. ed., Baltimore, Maryland.

Booze T F, Oehme F W. 1986. An Investigation of Metaldehyde and Acetaldehyde Toxicities in Dogs. Fund Appl Toxicol 6:440-446

Savides M C, Oehme F W, Leipold H W. 1985. Effects of Various Antidotal Treatments on Acetaminophen Toxicosis and Biotransformation in Cats. Am J Vet Res 46:1485-1489.

Savides M C, Oehme F W, Nash S L, Leipold H W. 1984. Toxicology and Biotransformation of Single Doses of Acetaminophen in Dogs and Cats. Toxicol Appl Pharmacol 74:26-34

Oehme F W, Dekker M. 1978. Toxicity of Heavy Metals in the Environment: Part 1, Part 2, New York.