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College of Veterinary Medicine

Anatomy & Physiology
College of Veterinary Medicine
Kansas State University

1620 Denison Avenue
228 Coles Hall
Manhattan, KS 66506-5802

Phone: 785-532-5666
Fax: 785-532-4557

AP@vet.k-state.edu

PBPK Textbook

Physiologically Based Pharmacokinetic (PBPK) Modeling: Methods and Applications in Toxicology and Risk Assessment, 1st Edition

Edited by Jeffrey W. Fisher, Jeffrey M. Gearhart, and Zhoumeng Lin 

Preface 

Chapter 1: Introduction to the field of PBPK modeling | Access Supplementary Materials

Chapter 2: Basics of pharmacokinetics (PK) | Access Supplementary Materials

Chapter 3: Fundamentals of PBPK modeling | Access Supplementary Materials

Chapter 4: PBPK modeling software platforms: general-purpose programming tools vs commercial software programs | Access Supplementary Materials

Chapter 5: PBPK model: Routes of Chemical Exposures across species | Access Supplementary Materials

Chapter 6: PBPK model: Distribution processes | Access Supplementary Materials

Chapter 7: PBPK model:  Metabolism | Access Supplementary Materials

Chapter 8: PBPK model: Excretion via urine, feces, and breath | Access Supplementary Materials

Chapter 9: Population PBPK Analyses Methods | Access Supplementary Materials

Chapter 10: PBPK model calibration, evaluation, and performance assessment | Access Supplementary Materials

Chapter 11: Local and global sensitivity, uncertainty, and variability analyses | Access Supplementary Materials

Chapter 12: Examples of use of PBPK modeling in Risk Assessment | Access Supplementary Materials

Chapter 13: Tox21, emerging methods. High-throughput data, IVIVE | Access Supplementary Materials