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College of Veterinary Medicine

Anatomy & Physiology
College of Veterinary Medicine
Kansas State University

1620 Denison Avenue
228 Coles Hall
Manhattan, KS 66506-5802

Phone: 785-532-5666
Fax: 785-532-4557



Major Research Directions

  • Developing and applying PBPK models for drugs in food-producing animals to predict tissue residues, drug withdrawal times, and milk discard times


  • Developing PBPK models for nanoparticles in laboratory animals and humans that can be used to predict tissue distribution across species and to help optimize the design of new nanoparticles
  • Applying PBPK models for drugs to help optimize treatment regimens in companion animals and humans
  • Integrating PBPK modeling and dose-response modeling to conduct probabilistic risk assessment for environmental chemicals and nanoparticles


  • Applying PBPK models to determine the role of physiological factors in the reported epidemiological association between exposure to environmental chemicals and adverse health effects