Research
Major Research Directions
- Developing and applying PBPK models for drugs in food-producing animals to predict tissue residues, drug withdrawal times, and milk discard times
- Developing PBPK models for nanoparticles in laboratory animals and humans that can be used to predict tissue distribution across species and to help optimize the design of new nanoparticles
- Applying PBPK models for drugs to help optimize treatment regimens in companion animals and humans
- Integrating PBPK modeling and dose-response modeling to conduct probabilistic risk assessment for environmental chemicals and nanoparticles
- Applying PBPK models to determine the role of physiological factors in the reported epidemiological association between exposure to environmental chemicals and adverse health effects
