Zhoumeng Lin

Zhoumeng Lin

Associate Professor

BMed, Preventive Medicine, Southern Medical University, 2009
PhD, Toxicology, The University of Georgia, 2013
Diplomate of American Board of Toxicology (DABT), 2017
Certified in Public Health (CPH) by National Board of Public Health Examiners (NBPHE), 2019
Certara Professional Certification, Population PK/PD Pharmacometrician (Level 1) using Phoenix NLME 8.0 and 8.1, 2019

Phone: 785-532-4087
Email: zhoumeng@ksu.edu
Lin Research Group Website


Computational Toxicology: Physiologically based pharmacokinetic (PBPK) modeling of nanomaterials and environmental chemicals in laboratory animals and humans. The goal is to apply these models to predict target tissue dosimetry and conduct interspecies pharmacokinetic extrapolation to aid risk assessment of nanomaterials and environmental chemicals.

Veterinary and Comparative Pharmacometrics: Development and application of physiologically based pharmacokinetic (PBPK), population-based pharmacokinetic (PopPK), and pharmacokinetic-pharmacodynamic (PKPD) models for veterinary drugs in food-producing animals and companion animals. The objective is to employ these models to estimate drug tissue residues and withdrawal times in food animals, and to help optimize drug therapeutic regimens across species.

Mechanistic Toxicology: Integration of neurobehavioral analysis, PBPK modeling, metabolomics, adverse outcome pathway (AOP) analysis, and molecular biology approaches to investigate mechanisms of toxicity of drugs and environmental chemicals, especially on the nervous system.


I teach an online course in Physiologically Based Pharmacokinetic Modeling (AP 873) for graduate students. This course is also available as continuing education for scientists in the pharmaceutical industry and governmental agencies, as well as for other non-traditional students through K-State Global Campus.


I am available to serve as Major Professor, Co-Major Professor, Advisor, PhD Dissertation Committee Member, MS Thesis Committee Member, and MPH Supervisory Committee Member. Please check with me about availability to serve during current academic period.


At Kansas State University (since February 2014; * Indicates corresponding author)


64. Chou WC, Lin Z*. (2020). Probabilistic human health risk assessment of perfluorooctane sulfonate (PFOS) by integrating in vitro, in vivo toxicity, and human epidemiological studies using a Bayesian-based dose-response assessment coupled with physiologically based pharmacokinetic (PBPK) modeling approach. Environment International, 137:105581. [PMID: 32087483] https://doi.org/10.1016/j.envint.2020.105581

63. Cheng YH, He C, Riviere JE, Monteiro-Riviere NA, Lin Z*. (2020). Meta-analysis of nanoparticle delivery to tumors using a physiologically based pharmacokinetic modeling and simulation approach. ACS Nano, 14(3): 3075-3095. [PMID: 32078303] https://doi.org/10.1021/acsnano.9b08142 [Featured at K-State Today and at KSU CVM’s Lifelines]

62. Lin Z*, Li M, Wang YS, Tell LA, Baynes RE, Davis JL, Vickroy TW, Riviere JE. (2020). Physiological parameter values for physiologically based pharmacokinetic models in food-producing animals. Part I: Cattle and Swine. Journal of Veterinary Pharmacology and Therapeutics, 43(5):385-420. [PMID: 32270548] https://doi.org/10.1111/jvp.12861

61. Kleinhenz MD*, Magnin G, Lin Z, Griffin J, Kleinhenz KE, Montgomery S, Curtis A, Martin M, Coetzee JF*. (2020). Plasma concentrations of eleven cannabinoids in cattle following oral administration of industrial hemp (Cannabis sativa). Scientific Reports, 10(1):12753. [PMID: 32728233] https://doi.org/10.1038/s41598-020-69768-4 [Featured at K-State Today ]

60. Lin YJ, Lin Z*. (2020). Probabilistic Risk Assessment of Combined Exposure to Bisphenol A and its Analogues by Integrating ToxCast High-Throughput In Vitro Assays with In Vitro to In Vivo Extrapolation (IVIVE) via Physiologically Based Pharmacokinetic (PBPK) Modeling. Journal of Hazardous Materials, 399, 122856. https://doi.org/10.1016/j.jhazmat.2020.122856

59. Bates JL, Karriker LA, Rajewski SM, Lin Z*, Ronette G, Li M, Riviere JE, Coetzee JF*. (2020). A study to assess the correlation between plasma, oral fluid and urine concentrations of flunixin meglumine with the tissue residue depletion profile in finishing age swine. BMC Veterinary Research, 16, 211. https://doi.org/10.1186/s12917-020-02429-w

58. KuKanich K, KuKanich B, Lin Z, Rankin AJ, Hanzlicek AS, Palerme JS, Bach J, Cook AK, Juracek A, Joo H. (2020). Clinical pharmacokinetics and outcomes of oral fluconazole therapy in dogs and cats with naturally occurring fungal disease. Journal of Veterinary Pharmacology and Therapeutics, in press.

57. Smith JS, Marmulak TL, Angelos JA, Lin Z, Rowe JD, Carlson JL, Shelver WL, Lee EA, Tell LA*. (2020). Pharmacokinetic parameters and estimated milk withdrawal intervals for domestic goats (Capra aegagrus hircus) after administration of single and multiple intravenous and subcutaneous doses of flunixin meglumine. Frontiers in Veterinary Science, 7:213. [PMID: 32509803] https://doi.org/10.3389/fvets.2020.00213

56. Xu N, Li M, Chou WC, Lin Z*. (2020). A physiologically based pharmacokinetic model of doxycycline for predicting tissue residues and withdrawal intervals in grass carp (Ctenopharyngodon idella). Food and Chemical Toxicology, 137, 111127. [PMID: 31945393] https://doi.org/10.1016/j.fct.2020.111127

55. Lin YJ*, Cheng CJ, Chen JW, Lin Z*. (2020). Incorporating exogenous and endogenous exposures into dietary risk assessment of nitrate and nitrite in vegetables: a probabilistic integrated toxicokinetic modeling approach. Journal of Agricultural and Food Chemistry, 68(4):1079-1090. [PMID: 31885263] https://pubs.acs.org/doi/10.1021/acs.jafc.9b06720


54. Chou WC, Lin Z*. (2019). Bayesian Evaluation of a Physiologically Based Pharmacokinetic (PBPK) Model for Perfluorooctane Sulfonate (PFOS) to Characterize the Interspecies Uncertainty between Mice, Rats, Monkeys, and Humans: Development and Performance Verification. Environment International, 129:408-422. [PMID: 31152982] https://doi.org/10.1016/j.envint.2019.03.058

53. Li M, Cheng YH, Chittenden JT, Baynes RE, Tell LA, Davis JL, Vickroy TW, Riviere JE, Lin Z*. (2019). Integration of Food Animal Residue Avoidance Databank (FARAD) empirical methods for drug withdrawal interval determination with a mechanistic population-based interactive physiologically-based pharmacokinetic (iPBPK) modeling platform: example for flunixin meglumine administration. Archives of Toxicology, 93(7):1865-1880. [PMID: 31025081] https://doi.org/10.1007/s00204-019-02464-z

52. Lin Z, He C, Magstadt DR, Cooper VL, Kleinhenz MD, Smith JS, Gorden PJ, Wulf LW, Coetzee JF*. (2019). Tissue residue depletion and estimation of extralabel meat withdrawal intervals for tulathromycin in calves after pneumatic dart administration. Journal of Animal Science, in press. [PMID: 31342061] https://doi.org/10.1093/jas/skz231

51. Li M, Mainquist-Whigham C, Karriker LA, Wulf LW, Zeng D, Gehring R, Riviere JE, Coetzee JF, Lin Z*. (2019). An integrated experimental and physiologically based pharmacokinetic modeling study of penicillin G in heavy sows. Journal of Veterinary Pharmacology and Therapeutics, 42(4):461-475. [PMID: 31012501] https://doi.org/10.1111/jvp.12766

50. Xu N, Li M, Fu Y, Zhang X, Dong J, Zhou S, Ai X*, Lin Z*. (2019). Effect of temperature on plasma and tissue kinetics of doxycycline in grass carp (Ctenopharyngodon idellus) after oral administration, Aquaculture, 511, 734204. https://doi.org/10.1016/j.aquaculture.2019.734204

49. Xu N, Li M, Fu Y, Zhang X, Ai X*, Lin Z*. (2019) Tissue residue depletion kinetics and withdrawal time estimation of doxycycline in grass carp, Ctenopharyngodon Idella, following multiple oral administrations. Food and Chemical Toxicology, 131, 110592. [PMID: 31220539] https://doi.org/10.1016/j.fct.2019.110592

48. DeLong R, Cheng YH, Pearson P, Lin Z, Wouda R, Mathew EN, Hoffman A, Coffee C, Higginbotham ML. (2019). Translating nanomedicine to comparative oncology: the case for combining zinc oxide nanomaterials with nucleic acid therapeutic and protein delivery for treating metastatic cancer. Journal of Pharmacology and Experimental Therapeutics, in press. [PMID: 31040175] https://doi.org/10.1124/jpet.118.256230

47. Clapham MO, Martin KL, Davis JL, Baynes RE, Lin Z, Vickroy TW, Riviere JE, Tell LA*. (2019). FARAD Digest: Extra-label Drug Use in Wildlife and Game Animals. Journal of the American Veterinary Medical Association, in press.

46. Sun X, Wang Y, Xia B, Li Z, Dai J, Qiu P, Ma A, Lin Z, Huang J, Wang J, Xie WB, Wang J. (2019). Methamphetamine produces cardiac damage and apoptosis by decreasing melusin. Toxicology and Applied Pharmacology, 378, 114543. [PMID: 30904475] https://doi.org/10.1016/j.taap.2019.03.015

45. Yang F, Lin Z, Riviere JE, Baynes RE. (2019). Development and application of a population physiologically based pharmacokinetic model for florfenicol and its metabolite florfenicol amine in cattle. Food and Chemical Toxicology, 126: 285-294. [PMID: 30825586] https://doi.org/10.1016/j.fct.2019.02.029

44. Zeng D, Lin Z*, Zeng Z, Fang B, Li M, Cheng YH, Sun Y. (2019). Assessing Global Human Exposure to T-2 Toxin via Poultry Meat Consumption Using a Lifetime Physiologically Based Pharmacokinetic Model. Journal of Agricultural and Food Chemistry, 67(5):1563-1571. [PMID: 30633497] https://doi.org/10.1021/acs.jafc.8b07133

43. Moczarnik JR, Berger DJ*, Noxon JO, LeVine DN, Lin Z, Coetzee JF, Mochel JP. (2019). Relative oral bioavailability of two amoxicillin-clavulanic acid formulations in healthy dogs: a pilot study. Journal of the American Animal Hospital Association, 55(1):14-22. [PMID: 30427713] https://doi.org/10.5326/JAAHA-MS-6872


42. Cheng YH, Riviere JE, Monteiro-Riviere NA, Lin Z*. (2018). Probabilistic risk assessment of gold nanoparticles after intravenous administration by integrating in vitro and in vivo toxicity with physiologically based pharmacokinetic modeling. Nanotoxicology, 12(5):453-469. [PMID: 29658401] https://doi.org/10.1080/17435390.2018.1459922

41. Li M, Gehring R, Riviere JE, Lin Z*. (2018). Probabilistic physiologically based pharmacokinetic model for penicillin G in milk from dairy cows following intramammary or intramuscular administrations. Toxicological Sciences, 164(1):85-100. [PMID: 29945226] https://doi.org/10.1093/toxsci/kfy067

40. Zeng D, Sun M, Lin Z*, Li M, Gehring R, Zeng Z*. (2018). Pharmacokinetics and pharmacodynamics of tildipirosin against Pasteurella multocida in a murine lung infection model. Frontiers in Microbiology, 9:1038. [PMID: 29867911] https://doi.org/10.3389/fmicb.2018.01038

39. Elwell-Cuddy T, Li M, KuKanich B, Lin Z*. (2018). The construction and application of a population physiologically based pharmacokinetic model for methadone in Beagles and Greyhounds. Journal of Veterinary Pharmacology and Therapeutics, 41(5):670-683. [PMID:
29923612] https://doi.org/10.1111/jvp.12676

38. Martin KL, Clapham MO, Davis JL, Baynes RE, Lin Z, Vickroy TW, Riviere JE, Tell LA*. Extra-label drug use in small ruminants. Journal of the American Veterinary Medical Association, 253(8):1001-1009. [PMID: 30272520] https://doi.org/10.2460/javma.253.8.1001

37. Xu X, Huang E, Luo B, Cai D, Zhao X, Luo Q, Jin Y, Chen L, Wang Q, Liu C, Lin Z, Wang H*, Xie WB*. (2018) Methamphetamine exposure triggers apoptosis and autophagy in neuronal cells through activating C/EBPβ related signaling pathway. The FASEB Journal, 32(12):6737-6759. [PMID: 29939784] https://doi.org/10.1096/fj.201701460RRR

36. Stafford EG*, Tell LA, Lin Z, Davis J, Vickroy TW, Riviere JE, Baynes RE. (2018). FARAD Digest: Management of fipronil contamination in layers. Journal of the American Veterinary Medical Association, 253(1):57-60. [PMID: 29911954] https://doi.org/10.2460/javma.253.1.57

35. Adamson SX, Lin Z, Chen R, Kobos LM, Shannahan J*. (2018). Experimental challenges regarding the in vitro investigation of the nanoparticle-biocorona in disease states. Toxicology in Vitro, 51:40-49. [PMID: 29738787] https://doi.org/10.1016/j.tiv.2018.05.003

34. Sikina ER, Bach JF*, Lin Z, Gehring R, KuKanich B. (2018). Bioavailability of suppository acetaminophen in healthy and hospitalized ill dogs. Journal of Veterinary Pharmacology and Therapeutics, 41(5):652-658. [PMID: 29756126] https://doi.org/10.1111/jvp.12664

33. Xiao N, Zhang F, Zhu B, Liu C, Lin Z, Wang H*, Xie WB*. CDK5-mediated Tau accumulation triggers methamphetamine-induced neuronal apoptosis via endoplasmic reticulum-associated degradation pathway. Toxicology Letters, 292:97-107. [PMID: 29705343] https://doi.org/10.1016/j.toxlet.2018.04.027


32. Lin Z* (2017). Advance in physiologically based pharmacokinetic modelling: from the organ level to sub-organ level based on experimental data. The Journal of Physiology, 595:7265-7266. [PMID: 29052221] https://doi.org/10.1113/JP275311

31. Zeng D, Lin Z*, Fang B, Li M, Gehring R, Riviere JE, Zeng Z*. (2017). Pharmacokinetics of mequindox and its marker residue 1,4-bisdesoxymequindox in swine following multiple oral gavage and intramuscular administration: an experimental study coupled with population physiologically based pharmacokinetic modeling. Journal of Agricultural and Food Chemistry, 65:5768-5777. [PMID: 28640606] https://doi.org/10.1021/acs.jafc.7b01740

30. Li M, Gehring R, Riviere JE, Lin Z*. (2017). Development and application of a population physiologically based pharmacokinetic model for penicillin G in swine and cattle for food safety assessment. Food and Chemical Toxicology, 107:74-87. [PMID: 28627373] https://doi.org/10.1016/j.fct.2017.06.023

29. Lin Z*, Jaberi-Douraki M, He C, Jin S, Yang RSH, Fisher JW, Riviere JE. (2017). Performance assessment and translation of physiologically based pharmacokinetic models from acslX to Berkeley Madonna, MATLAB, and R language: oxytetracycline and gold nanoparticles as case examples. Toxicological Sciences, 158:23-35. [PMID: 28402537] https://doi.org/10.1093/toxsci/kfx070

28. Du SH, Qiao DF, Chen CX, Chen S, Liu C, Lin Z, Wang H*, Xie WB*. (2017). Toll-like receptor 4 mediates methamphetamine-induced neuroinflammation through Caspase-11 signaling pathway in astrocytes. Frontiers in Molecular Neuroscience, 10:409. https://doi.org/10.3389/fnmol.2017.00409

27. Li Y*, Shi Z, Radauer-Preiml I, Andosch A, Casals E, Luetz-Meindl U, Cobaleda M, Lin Z, Jaberi-Douraki M, Italiani P, Horejs-Hoeck J, Himly M, Monteiro-Riviere NA, Duschl A, Puntes V, Boraschi D. (2017). Bacterial endotoxin (LPS) binds to the surface of gold nanoparticles, interferes with biocorona formation and induces human monocyte inflammatory activation. Nanotoxicology, 11:1157-1175. [PMID: 29192556] KSU news. https://doi.org/10.1080/17435390.2017.1401142

26. Xu X, Huang E, Tai Y, Zhao X, Chen X, Chen C, Chen R, Liu C, Lin Z, Wang H*, Xie WB*. (2017). Nupr1 modulates methamphetamine-induced dopaminergic neuronal apoptosis and autophagy through CHOP-Trib3-mediated endoplasmic reticulum stress signaling pathway. Frontiers in Molecular Neuroscience, 10:203. [PMID: 28694771] https://doi.org/10.3389/fnmol.2017.00203

25. Li B, Chen R, Chen L, Qiu P, Ai X, Huang E, Huang W, Chen C, Liu C, Lin Z, Xie WB*, Wang H*. (2017). Effects of DDIT4 in methamphetamine-induced autophagy and apoptosis in dopaminergic neurons. Molecular Neurobiology, 54:1642-1660. [PMID: 26873849] https://doi.org/10.1007/s12035-015-9637-9


24. Lin Z*, Gehring R, Mochel JP, Lavé T, Riviere JE. (2016). Mathematical modeling and simulation in animal health - Part II: principles, methods, applications, and value of physiologically based pharmacokinetic modeling in veterinary medicine and food safety assessment. Journal of Veterinary Pharmacology and Therapeutics, 39:421-438. [PMID: 27086878] https://doi.org/10.1111/jvp.12311

23. Lin Z, Vahl CI, Riviere JE*. (2016). Human food safety implications of variation in food animal drug metabolism. Scientific Reports, 6:27907. [PMID: 27302389] KSU news; AVMA news; AASV news; Farms.com news. https://doi.org/10.1038/srep27907

22. Lin Z, Monteiro-Riviere NA, Kannan R, Riviere JE*. (2016). A computational framework for interspecies pharmacokinetics, exposure and toxicity assessment of gold nanoparticles. Nanomedicine (Lond), 11:107-119. [PMID: 26653715] https://doi.org/10.2217/nnm.15.177

21. Lin Z, Monteiro-Riviere NA, Riviere JE*. (2016). A physiologically based pharmacokinetic model for polyethylene glycol-coated gold nanoparticles of different sizes in adult mice. Nanotoxicology, 10:162-172. [PMID: 25961857] https://doi.org/10.3109/17435390.2015.1027314 [Best Paper Award (Honorable Mention), Society of Toxicology Biological Modeling Specialty Section]

20. Lin Z, Cuneo M, Rowe JD, Li M, Tell LA, Allison S, Carlson J, Riviere JE, Gehring R*. (2016). Estimation of tulathromycin depletion in plasma and milk after subcutaneous injection in lactating goats using a nonlinear mixed-effects pharmacokinetic modeling approach. BMC Veterinary Research, 12:258. [PMID: 27863483] https://doi.org/10.1186/s12917-016-0884-4

19. Cai D, Huang E, Luo B, Yang Y, Zhang F, Liu C, Lin Z, Xie WB*, Wang H*. (2016). Nupr1/Chop signal axis is involved in mitochondrion-related endothelial cell apoptosis induced by methamphetamine. Cell Death and Disease, 7:e2161. [PMID: 27031958] https://doi.org/10.1038/cddis.2016.67

18. Chen R, Wang B, Chen L, Chen C, Huang E, Liu C, Lin Z, Xie WB*, Wang H*. (2016). DNA damage-inducible transcript 4 (DDIT4) mediates methamphetamine-induced autophagy and apoptosis through mTOR signaling pathway in cardiomyocytes. Toxicology and Applied Pharmacology, 295:1-11. [PMID: 26825372] https://doi.org/10.1016/j.taap.2016.01.017

17. Chen C, Qincao L, Xu J, Du S, Huang E, Liu C, Lin Z, Xie WB*, Wang H*. (2016). Role of PUMA in methamphetamine-induced neuronal apoptosis. Toxicology Letters, 240:149-160. [PMID: 26524635] https://doi.org/10.1016/j.toxlet.2015.10.020


16. Lin Z, Monteiro-Riviere NA, Riviere JE*. (2015). Pharmacokinetics of metallic nanoparticles. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 7:189-217. [PMID: 25316649] (Top Ten Accessed Publications in this journal in 2015) https://doi.org/10.1002/wnan.1304

15. Li M, Gehring R, Lin Z, Riviere JE*. (2015). A framework for meta-analysis of veterinary drug pharmacokinetic data using mixed effect modeling. Journal of Pharmaceutical Sciences, 104:1230-1239. [PMID: 25641543] https://doi.org/10.1002/jps.24341

14. Lin Z, Li M, Gehring R, Riviere JE*. (2015). Development and application of a multi-route physiologically based pharmacokinetic model for oxytetracycline in dogs and humans. Journal of Pharmaceutical Sciences, 104(1):233-243. [PMID: 25407474] https://doi.org/10.1002/jps.24244

13. Huang L, Lin Z, Zhou X, Zhu M, Gehring R, Riviere JE*, Yuan Z*. (2015). Estimation of residue depletion of cyadox and its marker residue in edible tissues of pigs using physiologically based pharmacokinetic modelling. Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment, 32:2002-2017. [PMID: 26414219] https://doi.org/10.1080/19440049.2015.1100330

12. Monteiro-Riviere NA*, Ortega MT, Choi K, Koci J, Lin Z, Jeffrey B, Riviere JE. (2015). Comparative in vitro cytotoxicity of 20 potential food ingredients in canine liver, kidney, bone marrow-derived mesenchymal stem cells and enterocyte-like cells. Applied in Vitro Toxicology, 1:276-288. https://doi.org/10.1089/aivt.2015.0020

11. He C, Lin Z, Robb SW, Ezeamama AE*. (2015). Serum vitamin D levels and polycystic ovary syndrome: a systematic review and meta-analysis. Nutrients, 7:4555-4577. [PMID: 26061015] https://doi.org/10.3390/nu7064555

10. Huang W, Xie WB, Qiao D, Qiu P, Huang E, Li B, Liu C, Wang Q, Lin Z, Wang H*. (2015). Caspase-11 plays an essential role in methamphetamine-induced dopaminergic neuron apoptosis. Toxicological Sciences, 145:68-79. [PMID: 25631491] https://doi.org/10.1093/toxsci/kfv014

At The University of Georgia (2009-2013)

9. Krishna S, Lin Z, de La Serre CB, Wagner JJ, Harn DH, Pepples LM, Djani DM, Weber MT, Srivastava L, Filipov NM*. (2016). Time-dependent behavioral, neurochemical, and metabolic dysregulation in female C57BL/6 mice caused by chronic high-fat diet intake. Physiology & Behavior, 157:196-208. [PMID: 26852949] https://doi.org/10.1016/j.neuroscience.2015.03.068

8. Krishna S, Keralapurath MM, Lin Z, Wagner JJ, de La Serre CB, Harn DA, Filipov NM*. (2015). Neurochemical and electrophysiological deficits in the ventral hippocampus and selective behavioral alterations caused by high-fat diet in female C57BL/6 mice. Neuroscience, 297:170-81. [PMID: 25849614] https://doi.org/10.1016/j.toxlet.2014.08.010

7. Qiao D, Xu J, Le C, Huang E, Liu C, Qiu P, Lin Z, Xie WB*, Wang H*. (2014). Insulin-like growth factor binding protein 5 (IGFBP5) mediates methamphetamine-induced dopaminergic neuron apoptosis. Toxicology Letters, 230:444-453. [PMID: 25127757]

6. Lin Z, Roede JR, He C, Jones DP, Filipov NM*. (2014). Short-term oral atrazine exposure alters the plasma metabolome of male C57BL/6 mice and disrupts α-linolenate, tryptophan, tyrosine and other major metabolic pathways. Toxicology, 326:130-141. [PMID: 25445803] https://doi.org/10.1016/j.tox.2014.11.001

5. Lin Z, Dodd CA, Xiao S, Krishna S, Ye X, Filipov NM*. (2014). Gestational and lactational exposure to atrazine via the drinking water causes specific behavioral deficits and selectively alters monoaminergic systems in C57BL/6 mouse dams, juvenile and adult offspring. Toxicological Sciences, 141:90-102. [PMID: 24913803] https://doi.org/10.1093/toxsci/kfu107

4. Lin Z, Fisher JW, Wang R, Ross MK, Filipov NM*. (2013). Estimation of placental and lactational transfer and tissue distribution of atrazine and its main metabolites in rodent dams, fetuses, and neonates with physiologically based pharmacokinetic modeling. Toxicology and Applied Pharmacology, 273:140-158. [PMID: 23958493] https://doi.org/10.1016/j.taap.2013.08.010

3. Lin Z, Dodd CA, Filipov NM*. (2013). Short-term atrazine exposure causes behavioral deficits and disrupts monoaminergic systems in male C57BL/6 mice. Neurotoxicology and Teratology, 39:26-35. [PMID: 23770127] https://doi.org/10.1016/j.ntt.2013.06.002

2. Lin Z, Dodd CA, Filipov NM*. (2013). Differentiation state-dependent effects of in vitro exposure to atrazine or its metabolite diaminochlorotriazine in a dopaminergic cell line. Life Sciences, 92:81-90. [PMID: 23142650] https://doi.org/10.1016/j.lfs.2012.10.027

1. Lin Z, Fisher JW, Ross MK, Filipov NM*. (2011). A physiologically based pharmacokinetic model for atrazine and its main metabolites in the adult male C57BL/6 mouse. Toxicology and Applied Pharmacology, 251:16-31. [PMID: 21094656] https://doi.org/10.1016/j.taap.2010.11.009