July 2016 - Vol. 11, No. 7
OIE supports twinning program between CVM and Sokoine University
The College of Veterinary Medicine at Kansas State University is pleased to announce the establishment of a twinning partnership with Sokoine University of Agriculture Faculty of Veterinary Medicine in Morogoro, Tanzania, which has been formed through a program administered by the World Organisation for Animal Health (OIE) in Paris, France.
The Veterinary Education Establishment Twinning Program was established by the OIE in 2013 and has since supported partnerships between well-matched, eligible veterinary education establishments. The program aims to strengthen veterinary education by establishing partnerships which lead to exchanges of ideas, knowledge and experiences for students and faculty.
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The ultimate program objective is to ensure that veterinary graduates all over the world are equipped with the competencies needed to support their national veterinary services. The OIE has committed a $457,213 grant for the twinning project between Kansas State University and Sokoine University.
“The OIE believes that strengthening the capacities of its Member Countries and, in particular, ensuring that veterinarians possess an adequate level of education, are fundamental,” explained Dr. Monique Eloit, director general of the OIE. “Veterinary students will become the professionals who will ensure that their countries meet the health challenges of tomorrow. The OIE Veterinary Education Twinning Programme, in addition to the OIE recommendations and guidelines on veterinary education were developed to ultimately improve the provision of high quality veterinary education worldwide.”
The partnership with Kansas State University will strengthen the curriculum and educational resources at Sokoine University of Agriculture Faculty of Veterinary Medicine and provide opportunities for faculty and students from both universities to be exposed to global health challenges and veterinary production systems in a different cultural and socioeconomic setting.
“International collaborations are critical to the future of our profession and our ability to educate the next generation veterinary workforce,” said Dr. Tammy Beckham, dean of the Kansas State University College of Veterinary Medicine. “We have been working with the faculty at Sokoine University since last October to develop mutually beneficial objectives for this project, an appropriate time frame, and a work plan. We’re very excited by the opportunities that will be available for our faculty and students.”
Dr. Keith Hamilton, executive director of International Programs, was instrumental in identifying and developing the partnership with Sokoine University.
“As well as supporting curriculum development at Sokoine University, the partnership will allow faculty and students from KSU and SUA to gain a global perspective with exposure to veterinary medicine and farming systems in a new country,” Dr Hamilton said. “The next generation of veterinarians will need a global perspective to address global health challenges and to ensure that the veterinary profession remains relevant.”The initial project will be supported by the OIE for three years, however, Sokoine University and Kansas State University have committed to maintaining a long-term relationship, which is reflected in the official agreement between the two partners. The partners will explore multiple opportunities for supporting long-term collaboration and seek future funding for joint research projects as well as develop mechanisms for ongoing exchanges of faculty and students to further enrich career development and educational experiences.
ICCM study reevaluates food safety assessment method
Research by Kansas State University's Institute of Computational Comparative Medicine is challenging conventional thought regarding human food safety and drug residues found in cattle and swine tissues.
In the study "Human Food Safety Implications of Variation in Food Animal Drug Metabolism" published recently in Nature's Scientific Reports, Kansas State University researchers Drs. Zhoumeng Lin, Christopher Vahl and Jim Riviere found that diseases can dramatically influence the type of drug residue found in tissues of food animals that are tested by regulatory agencies in monitoring human food safety.
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“While this is just one study, we believe our work could have significant impact on food safety in the future,” said Dr. Riviere, director of the ICCM. Dr. Riviere also is a university distinguished professor, Kansas Bioscience eminent scholar, the MacDonald chair in the College of Veterinary Medicine, and an elected member of the National Academy of Medicine.
Withdrawal times — the time from last drug administration to slaughter — are determined in healthy animals during the drug development process assuming that the ratio of the marker residue to the total residue produced is constant. This "marker residue ratio" is then used to set legal tissue tolerances in food safety inspection programs, but diseases in treated animals may alter this ratio, said Dr. Lin, an assistant professor of anatomy and physiology.
The College of Veterinary Medicine at Kansas State University has announced the hiring of Dr. Peggy Schmidt as its new associate dean for academic programs and student affairs, joining the college Sept. 6. Dr. Schmidt has been a faculty member in veterinary education for 12 years, and served as an academic director for nine of those years. She currently serves Western University of Health Sciences as director of outcomes assessment. Prior to this role, Dr. Schmidt was the director of the year 4 curriculum. She is also an associate professor of population health and epidemiology.
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Dean Tammy Beckham said, “Dr. Schmidt brings an outstanding skill set and a great deal of passion for promoting excellence in veterinary education. Through this position, the College of Veterinary Medicine at K-State will have the opportunity to grow and enhance our nationally recognized professional program. Dr. Ronnie Elmore, associate dean for admissions and diversity programs, will continue to lead admissions and diversity for our DVM program.”
“I have always taken great pride in being a teacher, administrator, mentor, and motivator, and I look forward to helping the College of Veterinary Medicine at Kansas State University strive for academic excellence,” Dr. Schmidt said. “There are great challenges ahead in veterinary education, but the faculty, staff and students at K-State have the creative energy to overcome those challenges. I take great satisfaction in making contributions to the success of a veterinary program and am excited to become a part of the rich history and bright future of K-State.”
Dr. Schmidt earned a bachelor’s degree in animal science with meat animal emphasis at the University of Wisconsin-River Falls in 1993. She then earned a DVM at the University of Minnesota in 1997. After graduating, she practiced as an associate veterinarian at Tri-County Veterinary Clinics in Taunton and Dawson, Minnesota until 2002. She then returned to college and earned a master’s degree in veterinary preventive medicine at the Iowa State University in 2004, also serving as an instructor for its College of Veterinary Medicine.
Dr. Schmidt became board-certified as a diplomate of the American College of Preventive Veterinary Medicine in 2006. She also earned multiple certifications for instruction in agroterrorism preparedness curriculum in 2005 and 2006 at the University of California, Davis. She won the Carl Norden-Pfizer Distinguished Teacher Award at Western University of Health Sciences in 2008. She has been a member of American Association of Bovine Practitioners, American Association of Food Hygiene Veterinarians, American Association of Swine Veterinarians, Association of Veterinary Epidemiology and Preventive Medicine, American Veterinary Medical Association, California Veterinary Medical Association, Evidence Based Veterinary Medical Association, Veterinary Education Collaborative and Teaching Academy of the Consortium of West Region Colleges of Veterinary Medicine.
Dr. Schmidt and her husband, Gary, have one daughter, Emma.
A pair of UK and US security experts called for greater cooperation between veterinarians and international agencies toward reducing biological threats and improving international security during a recent visit to the College of Veterinary Medicine at Kansas State University.
The experts, Andrew Weber, former assistant secretary of defense and deputy coordinator for Ebola response at the U.S. Department of State; and David Elliott, a leader in cooperative threat reduction at Defense Science and Technology Laboratories, UK government, spoke about the relationship between global security and outbreaks of animal and zoonotic diseases.
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Weber, who had been a key player in dismantling the former USSR’s bioweapons program, highlighted the potential use of animal pathogens and zoonotic agents (pathogens that can cause disease in humans as well as animals) as bioweapons should they fall into the wrong hands.
“All veterinarians are security people,” Weber said. “We depend on them to keep us safe from infectious diseases of both humans and animals. I encourage veterinarians to think globally about their responsibilities which can make the world a safer place, and encourage emerging leaders in the veterinary profession to consider careers in improving global health security.”
While addressing the potential use of animal pathogens by terrorists, Weber pointed out how cooperation and laboratory capacity building can limit access to these agents.
“In the case studies we have of terrorist groups seeking to develop biological weapons, the one technical hurdle they seem to fail at repeatedly is obtaining the pathogen – obtaining the starter culture,” Weber said. “We have an opportunity to reduce the risk of terrorism by consolidating or reducing the number of laboratories that have Bacillus anthracis (anthrax).”
Elliott explained another way in which veterinary medicine can have a positive impact on global security.
“If you’re in the veterinary sector, look at some of the good this sector can do,” Elliott said. “For example, increasing productivity, helping people to manage healthier livestock – all of that tends to raise living standards. By projecting your expertise abroad, you can make a positive impact on people’s lives, and that reduces the drivers of conflict and civil unrest.”
Elliott also talked about benefits of working with intergovernmental animal health agencies, the World Organisation for Animal Health (OIE) and the United Nations Food and Agricultural Organization (FAO). He highlighted that the sustainable strengthening of health services worldwide promotes benefits for society at the same time as reducing threats from pathogens whether they have a natural or unnatural origin.
Elliott listed several ways these agencies utilize veterinary experts for capacity building, including international twinning programs for veterinary colleges and laboratories, assessments of national veterinary services, veterinary infrastructure capacity building, and training in good emergency management practice for animal health and food related emergencies through the FAO’s Crisis Management Centre. He also emphasized the importance of the One Health initiative.
The office of International Programs in the College of Veterinary Medicine sponsored the panel discussion.
“We have invited these two guests to our campus to highlight that cooperation between the security and veterinary sectors can minimize all biological threats whether they have a natural or unnatural origin,” said Dr. Hamilton, executive director for International Programs.
“In addition to highlighting the wealth of knowledge and capacity available at the College of Veterinary Medicine, which can support biological threat reduction activities, this was an excellent opportunity for our campus to engage and learn from a pair of individuals with firsthand knowledge and experience,” said Dr. Tammy Beckham, dean of the College of Veterinary Medicine.
Weber served until October 2014 as assistant secretary of defense for Nuclear, Chemical and Biological Defense Programs. In this capacity he focused on preventing, protecting against, and responding to Weapons of Mass Destruction and terrorism threats. He supported international efforts to eliminate Syrian and Libyan chemical weapons, and strengthen global health security. In October 2014 President Obama asked Weber to serve as Deputy Coordinator for the Ebola response at the US Department of State.
Elliott has spent several years with the UK’s cooperative threat reduction program, working closely with his counterparts from the USA and Canada, and other countries in the G7 Global Partnership against weapons of mass destruction. He has been a key advocate of investing in animal and human health systems to reduce biological threats from all quarters, including natural, accidental and intentional releases. On the ground he has been responsible for establishing and managing a range of capacity building initiatives across North Africa, the Middle East and Asia.
The College of Veterinary Medicine at Kansas State University has named Dr. Hans Coetzee (pronounced could-see) as its new department head for the Department of Anatomy and Physiology. Dr. Coetzee returns to the College of Veterinary Medicine where he was on the faculty from October 2005 to July 2011, before accepting a position with Iowa State University’s College of Veterinary Medicine, where he was a professor and section leader for its Pharmacology Analytical Support Team. He will join Kansas State University Oct. 1.
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Dean Tammy Beckham said, “We are very pleased to have Dr. Coetzee return to Kansas State University and assume a leadership role in our college. He has a great wealth of experience as researcher, instructor and administrator in cattle health, animal welfare and pharmacology. Dr. Coetzee is committed to institutional success with a sound record of leadership in the areas of research support and sponsored funding, institutional service, outreach, teaching, and professional practice.”
“It is very exciting to have a chance to come back to Kansas State University and an honor to have been selected to serve as the Department Head for Anatomy and Physiology,” Dr. Coetzee said. “I am humbled to join a Department where there are many talented faculty members who do outstanding work teaching foundational skills to the next generation of veterinarians. Researchers here are also focused on solving some of the world’s most complex biomedical challenges at a time when competition for funding resources has never been more intense. I look forward to working with faculty to identify new opportunities to better meet the needs of our veterinary students and to expand our research portfolio.”
Dr. Coetzee earned a Bachelor of Veterinary Science Degree at the University of Pretoria, Onderstepoort, South Africa in 1996. He earned a doctorate in veterinary microbiology in the Department of Veterinary Microbiology and Preventative Medicine at Iowa State University in 2005.
Dr. Coetzee became board-certified as a diplomate of the American College of Veterinary Clinical Pharmacology in 2006, and as a diplomate of the American College of Animal Welfare in 2014. He also earned a certificate Cattle Health and Production from the Royal College of Veterinary Surgeons in London in 2000 and is a European Specialist in Animal Welfare Science, Ethics and Law.
Dr. Coetzee was a mixed animal practitioner from August 1996 to May 2000 at the Riada Veterinary Clinic, Ballymoney, Co. Antrim, Northern Ireland. From 2000 to 2002, he was a veterinary adviser for the Research and Development Division of Norbrook Laboratories Ltd. In Northern Ireland. He served two years as an adjunct professor and university veterinarian at Iowa State University before joining the faculty at Kansas State University in 2005. He has published over 100 peer-reviewed papers and received more than $7 million in research funding.
Dr. Coetzee is a member of the American Association of Bovine Practitioners, American Academy of Veterinary Pharmacology and Therapeutics, American Veterinary Medical Association, American Society of Animal Science, American Dairy Science Association, Academy of Veterinary Consultants and American Association of Swine Practitioners. He has been presented with the 2014 American Association of Bovine Practitioners Award of Excellence, 2014 Zoetis Award for Veterinary Research Excellence, 2006 Novartis Teaching Excellence Award in recognition of outstanding instruction of third year students, Fort Dodge Animal Health Fellowship in Veterinary Medicine, 2004 and Northern Ireland Veterinarian of the Year Award in 2000.
In his free time he enjoys spending time with his wife, Tiffany, and his twin daughters, Scarlett and Anabelle.
Researchers in the College of Veterinary Medicine at Kansas State University have teamed up with the Lawrence Livermore National Laboratory in California to evaluate the impact and association of microbiomes in connection with two of the most devastating viral diseases in swine.
“Understanding how the microbiome impacts health and disease in swine is a relatively new field of study,” said Dr. Megan Niederwerder, the lead author and an assistant professor in the Department of Diagnostic Medicine/Pathobiology and Kansas State Veterinary Diagnostic Laboratory.
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Dr. Niederwerder explained the term microbiome refers to the community of microorganisms living within or on the surface of our bodies. The gastrointestinal tract houses the greatest proportion of these microorganisms.
“Previous microbiome associations have been linked in humans to obesity, autoimmune and infectious diseases, immune response and cancer,” Dr. Niederwerder said. “Detailed investigations into understanding how the gastrointestinal microbiome impacts health and disease in animals are increasing. In our work, we have looked at microbiome diversity and composition in nursery pigs in association with clinical disease and growth performance after virus infection.”
The study, entitled “Microbiome associations in pigs with the best and worst clinical outcomes following co-infection with porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus type 2 (PCV2)” was published in the May 2016 issue of Veterinary Microbiology. These viral infections have caused billions of dollars in losses to swine producers over the last 25 years.
“We looked at nursery pigs with systemic viral infections and found that increased diversity of the microbiome and the presence of specific bacteria, such as nonpathogenic E. coli, were associated with improved outcome,” Dr. Niederwerder said. “Greater diversity of the microbiome seems to lead to a better response to infection for swine. Our ultimate goal would be to develop ways in the future to modulate the microbiome and improve response to virus infection.”Co-authors on the study included Dr. Bob Rowland and Dr. Giselle Cino-Ozuna from Kansas State University, and Dr. Crystal Jaing, Dr. Kevin McLoughlin, and James Thissen from Lawrence Livermore National Laboratory.
Two veterinary students will work on research projects overseas as recipients of 2016 international student travel awards from the office of International Programs. This year’s recipients are both third-year veterinary medicine students. Sohaila Jafarian, Manhattan, will work on a One Health water sanitation project in Managua, Nicaragua. Marie Keith, Maple Hill, will work on a rabies project at the Division of Infectious Diseases at the Chinese Center for Disease Control and Prevention in Beijing.
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The objective of the College of Veterinary Medicine’s travel awards program is to facilitate international experiences and make a positive contribution to animal and public health. Students must apply for the awards and demonstrate a need based on “novel, brilliant, interesting and worthwhile” ideas.
“We’ve focused on providing fewer but larger travel awards this year, with an emphasis on supporting projects that will not only be relevant to the student’s Doctor of Veterinary Medicine studies, but also provide a benefit to the host country,” said Dr. Keith Hamilton, executive director for the college’s international programs. “We had eight excellent applications this year and it was difficult to make a decision on the winners. We’re very pleased with the amount of interest from the students and the quality of their applications.”
An “endearing” essay about the history of some favorite fuzzy pets recently earned a third-place prize for Kelsey Madden, Olathe, Kansas, in the 2016 J. Fred Smithcors Student Veterinary History Essay Contest.
Madden, who just finished her first year of studies in the College of Veterinary Medicine at Kansas State University, also earned an $800 award for the essay, which she had revised from a paper for history of veterinary medicine class, called “The Guinea Pig: Endearing, Enduring or Both?”
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The essay will be published in the May 2017 issue of the semi-annual journal, Veterinary Heritage.
“I have two pet guinea pigs, Betty and Alice, and I was originally going to write about something else, but realized there was a lot of good information I could draw from,” Madden said. “I learned that over the course of history, guinea pigs have been used in experiments that led to 23 different Nobel Prizes. There are countless factoids related to these animals, like the discovery of circulation in the 16th century.”
Madden, who also has a horse, said she would one day like to work in a mixed animal veterinary practice after she graduates with her Doctor of Veterinary Medicine degree from Kansas State University.
Dr. Howard Erickson, professor emeritus in anatomy and physiology, teaches the history course and routinely encourages his students to submit their research papers for the Smithcors Essay contest.
“I suggest topics for the students, but encourage them to pick a topic they are passionate about – really interested in – and this is what Kelsey did,” Dr. Erickson said. “Kelsey also had a very unique title for her paper. It included excellent figures and was very well-referenced.”
The contest is named in honor of J. Fred Smithcors for his many contributions to veterinary history, including as founder of the American Veterinary Medical History Society, the author of several books on veterinary history, and as an educator, publisher and editor. Since 2012, grants from the Donaldson Charitable Trust have made it possible to award four prizes in honor of Dr. Elizabeth Atwood Lawrence, twice AVMHS president and former essay contest judge.
CVM's Strategic Planning initiative
The College of Veterinary Medicine announced a new strategic planning initiative in May. In the video, Dean Tammy Beckham explains why participation is important from all the college's stakeholders. What does the future of veterinary education, animal health, teaching, research and service look like? Where do we need to be? Your participation and thoughtful opinions can help make our college the elite institution that it should be.
The CVM also held a picnic to promote awareness and participation in the Strategic Planning efforts on June 29. Faculty, staff and students attended and received a special goody bag with "Creating Our Future Together" items. (Video produced by Kent Nelson; Pictures by Audrey Hambright.)
It is just before midnight, and a full moon is shining its strong beam, helping Kansas State University’s Dr. David Eshar and his colleagues find and sample wild common chameleons (or Mediterranean chameleons) in Israel. “The chameleons are diurnal animals that spend the nights sleeping mainly on Jujube and Carob trees, that are now in full blossom and attracting their prey of various insects,” explained Dr. Eshar, assistant professor of wildlife and zoo medicine in the College of Veterinary Medicine.
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“Surveying the area by foot and on vehicles, shining a strong beam of light at the trees can help locate the sleepy chameleons.” Not an easy task as they are well camouflaged even when asleep looking like the leaves on the tree branch they are on.
Dr. Eshar’s research is being performed in collaboration with Dr. Boaz Shacham, a herpetologist from the Hebrew University, Jerusalem Israel, and researchers from the Kimron Veterinary Institute, Israel. The researchers aim to investigate the potential presence of several pathogens, such as viruses and bacteria in wild common chameleons.
“The findings of this study will not only enhance the knowledge about the medicine of this reptile species, but will also determine how common these pathogens are in the environment,” Dr. Eshar said.
“This is part of the One Health concept, where wild animals neighboring humans are tested for carrying diseases that can potentially harm people and their livestock.”
Dr. Eshar has been in Israel since June 17 and will return to Kansas State University on July 10. While on this project, Dr. Eshar is also mentoring a student from Koret Veterinary School, Hebrew University, on his Doctor of Veterinary Medicine degree thesis.
CEEZAD Transboundary Animal Disease Summer Program Provides a Unique Opportunity for Future Veterinary Professionals
Ten future veterinary professionals with an interest in transboundary disease research took part in a two-week training program conducted by the Center of Excellence for Emerging Zoonotic and Animal Diseases (CEEZAD) at Kansas State University in coordination with the Biosecurity Research Institute (BRI). The program involved one week of exposure to operations, safety techniques and laboratory principles of high-containment biosafety level 3 (BSL-3) work at the BRI followed by a second week of visits to institutions involved in the animal health industry and lectures.
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Dr. Steven Ellsworth, assistant director of CEEZAD, told participants they were training for careers in a field that is important to the protection of the nation's food animal industry, and thus to the food supply.
"All we work on and fund is research on diseases that are exotic to the United States and that the Department of Homeland Security and the USDA are concerned could get into the United States," Dr. Ellsworth told the participants. "What can we do to prevent these diseases from getting into the U.S., or contain an outbreak?"
Dr. Ellsworth said CEEZAD is also tasked with training a specialized workforce to help defend American agricultural systems and to help the transition of the Plum Island Animal Disease Center (PIADC) to the National Bio and Agro-defense Facility (NBAF), a task they could find themselves pursuing in their professional careers.
Dr. Steven Higgs, director of the BRI, told participants they were studying at "one of the country's most modern laboratories to deal with animal diseases." The BRI is a level 3 facility, the second most secure designation.
The students came to Manhattan with a variety of hopes and aspirations, although most envision a future in some aspect of disease research.
Dr. Tessa LeCuyer, for example, is a veterinarian who works in a lab while combining her clinical residency with a doctoral program at Washington State. She saw particular benefit in learning the level 3 BSL procedures in place at the BRI. "We always have the potential to come across higher-consequence pathogens," she explained.
Sarah Kezar has been fascinated by biomechanics since high school which has led her to both a BS from University of Virginia and an MS from University of Alabama-Birmingham in biomedical engineering. Currently, as a first-year Doctor of Veterinary Medicine student at Auburn University, she enrolled in the summer program in the hope of enriching her knowledge of genetic engineering, particularly with respect to the One Health concept.
Jonathan Miller, who is about to begin veterinary school at Washington State, hopes to do research in infectious diseases. "CEEZAD's mission is directly in line with my career goals," he said, noting the training and networking possibilities he hoped to take advantage of during the summer program.
Marie Keith, a third-year veterinary student at Kansas State University, was drawn to the program due to an interest in transboundary diseases. She hopes to pursue a career in outbreaks investigation, possibly with the CDC or WHO. She is combining her veterinary studies with a focus on public health.
Students spent the first week of the program at the BRI practicing how to operate in high-consequence animal disease environments. This included sessions designed to familiarize them with how to safely wear protective clothing and how to use personal disinfection techniques in BSL-3 facilities. They also spent a session practicing the safe preparation, handling and storage of laboratory agents, as well as the safe disposal of lab materials.
All of the participants praised the concluding mini-symposium, which brought in experts on emerging and zoonotic diseases for a discussion of the latest developments in their field. Those experts included a panel of authorities such as Dr. Heinz Feldmann (NIH-NIAID, Rocky Mountain Laboratory); Dr. Don King (The Pirbright Institute, UK), Dr. Luis Rodriguez (Plum Island Animal Disease Center), Dr. Brian Bird (University of California-Davis), Dr. Paul Gibbs (Kansas State University), Dr. Michelle Colby (Department of Homeland Security), Dr. Marty Vanier (Department of Homeland Security), Dr. Ron Trewyn (Kansas State University) and Dr. Beth Lautner (USDA-APHIS), who discussed topics ranging from the West African Ebola epidemic, Foot-and-Mouth Disease outbreaks, African swine fever research, Rift Valley fever vaccine and an update on progress toward the opening of the National Bio and Agro-defense Facility (NBAF), which is being constructed on the Kansas State University campus. The students were also able to participate in classroom lectures given by experts such as Dr. Young Lyoo from Konkuk University and Dr. Larry Barrett from the Department of Homeland Security as well as local experts from the College of Veterinary Medicine at Kansas State University which included Dr. Alfonso Clavijo, Dr. A. Sally Davis, and Dr. Lina Mur.
The idea was to grow the field of future veterinary health researchers utilizing funding provided by the Department of Homeland Security.
The CVM's office of International Programs announces the launch of the "Veterinarians around the world" photo competition. The theme for the competition is international veterinary medicine. Entries should capture efforts to improve animal health, public health or wildlife/ecosystem health; food security (sustainable production systems); food safety; capacity building; animal welfare; or biological threat reduction. Any other subjects relating to international veterinary medicine will also be considered.
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Undergrad students receive Histochemical Society Capstone Grants for research projects under Dr. A. Sally Davis
A pair of undergraduate students at Kansas State University, Kaitlynn Bradshaw and MaRyka Smith, have successfully applied for research grants to support their projects under the mentorship of Dr. A. Sally Davis, an assistant professor of experimental pathology in the College of Veterinary Medicine. The $500 awards are provided through the Histochemical Society’s new Capstone Grant program, which has the objective of promoting the use of immunohistochemistry or other histochemical techniques in biological research. Bradshaw and Smith are two of the first three students to receive one of these grants.
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Bradshaw, a junior in biology, is originally from Hill City, Kansas. Her project is entitled "Calcofluor White Labeling of Pneumocystis.” This project involves the fungus Pneumocystis known for its ability to cause life threatening pneumonia in immunocompromised individuals.
“For years, calcofluor white has been used to stain tissues to detect Pneumocystis,” Bradshaw wrote in her application. “It had long been assumed that this fluorescent dye was staining chitin. However, recent sequencing of the genome of Pneumocystis has determined that this fungus produces no genes capable of synthesizing chitin.”
The purpose of Bradshaw's research project is to determine what it is that calcofluor white is staining. She plans to work towards earning a master's degree in the field of pathology.
Smith, Hoyt, Kansas, is a senior majoring in animal sciences and industry. Her project is entitled, “Mechanisms of Acute Kidney Injury in RVFV Infected Ruminant Tissues.” This project is a continuation of recently published work on the development of cattle and sheep Rift Valley fever virus challenge models for vaccine efficacy testing in which renal damage was observed.
“Rift Valley fever is a mosquito-borne viral disease that causes large economic losses in Africa and the Middle East,” Smith wrote in her application. “There are currently no commercially available vaccines for humans, and those available for livestock are difficult to administer and can be dangerous to young and gestating animals. My project aims to determine the mechanism of renal damage during Rift Valley fever in ruminants.”
MaRyka is finishing her prerequisites and will be applying to veterinary school this fall. Her ultimate goals include working in the pathology of large animals.
“I’m thrilled that Katie and MaRyka have both made the transition from practicing experimental pathology techniques to leading their own research projects in which they can pursue interesting unanswered questions regarding infectious disease,” Dr. Davis said. “I look forward to their discoveries and their communication of them to the wider scientific community. These awards from HCS are confirmation that Kansas State University is strong in its ability to provide undergraduate research opportunities, and I am proud to be part of that tradition.”
The Histochemical Society is an organization of scientists sharing a passion for the development and use of visual techniques that provide biochemical and molecular information about the structure and function of cells, tissues and organs and for the dissemination of this knowledge through education and outreach. The society fulfills its mission through publishing the Journal of Histochemistry and Cytochemistry, and through the management of annual meetings and short courses.
The Veterinary Medical Alumni Association presents its annual alumni recognition awards at the 78th Annual Conference for Veterinarians and the Kansas Veterinary Medical Association presents its annual awards the next day at the conference. Find out who this year's winners are below.
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The KSU Foundation recently announced the promotion of Eric Holderness to senior director of development for the College of Veterinary Medicine. Holderness joined the foundation in 2013, where he served as a development officer for the College of Arts and Sciences and rose to the position of director of development for the college. As a key member of the College of Arts and Sciences development team, he helped the team achieve three straight years of record fundraising success. Prior to joining the foundation, Holderness worked with K-State Athletics and the Ahearn Fund.
Holderness received a master’s degree in college student personnel in 2011 from Kansas State University and his bachelor’s in advertising from K-State in 2009. He achieved the Certified Fundraising Executive (CFRE) certification in 2015.
“We are pleased to welcome Eric in his new role at the College of Veterinary Medicine,” said Dr. Tammy Beckham, dean of the college. “A key component to the achievements of this college, now and in the future, is a strong philanthropic foundation, and we look forward to Eric’s leadership in this capacity.”
Philanthropic contributions to K-State are coordinated by the Kansas State University Foundation. The foundation staff works with university partners to build lifelong relationships with alumni, friends, faculty, staff and students through involvement and investment in the university.
AVMA Alumni Receptioion
Monday, Aug. 8, 7-9 p.m.
Dr. Linda Johnson, DVM class of 1983, will be presented with an Alumni Recognition Award. Please join us.
Questions about Alumni or CE events?
Pet Friendly License Plate program in Kansas
The College of Veterinary Medicine has a new way to support shelter medicine in Kansas. The Pet Friendly license plate is available to Kansas residents statewide by visiting your local Kansas county treasurer's office.
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More activities and accomplishments in the College of Veterinary Medicine:
Drs. Laura Armbrust, Paxton Harness, Mary Lynn Higginbotham, Susan Nelson, Raelene Wouda, Marjory Artzer, Lisa Pohlman, Adi Naor, David Biller: “Evaluation of subcutaneous masses utilizing shear wave elastography in dogs.” Mark Derrick Canine Research funds - $7,620.
Dr, Thomas Schermerhorn: “Relationships between serum tonicity and hyperglycemia in diabetic dogs.” Mark Derrick Canine Research funds - $8,950. He also presented at the American College of Veterinary Internal Medicine forum in Denver. “Hypertonicity and its complications in diabetes” and “Diagnosis of adrenal disease in dogs.”
Dr. Mike Apley presented at the Vermont Veterinary Medical Association in Burlington, Vermont. Topics: Antibiotic resistance and antibiotic use in animals and humans; The veterinary feed directive and other upcoming changes in regulations for drug use in food animals; A joint one-health session on antimicrobial resistance; and Evaluating clinical signs and lung lesions in calves with bovine respiratory disease. He also presented at the Cowboy College in Des Moines, Iowa. Topic: Vaccination programs, antibiotic decisions, and herd health.
The Shelter Medicine Mobile Surgery Unit continues to receive media press. The Ottawa Herald published, “Mobile Surgery Unit aids Prairie Paws and other shelters.” The mobile unit spent 218 days on the road in its first year regularly visiting 12 area shelters and performing 3,499 spay/neuter surgeries.
Anna “Clarisse” Leppien, in Central Preparation, passed the exam June 21 and is now a Certified Registered Central Service Technician (CRCST).
Dr. David Eshar was elected by his peers to become the Chair of the Small Mammal sub-specialty of the European College of Zoological Medicine (ECZM) and a member of the Executive Committee of the college.
Dr. James Carpenter was named as one of the 15 Most Influential Veterinarians in 2016 by veterinarianedu.org.
Dr. A. Sally Davis was awarded the following grant/fellowships in June 2016: Kansas State University Office for the Advancement of Women in Science and Engineering’s ADVANCE Distinguished Lecture Series grant, $1,200; University of Kansas NIH COBRE Protein Structure and Function pilot project “Characterization of protease TMPRSS2 and its interaction with influenza A,” $41,000 direct costs; and the Big 12 fellowship with mentoring component application to be mentored by Gillian Air, University of Oklahoma Health Sciences Center entitled “Elucidating Rift Valley fever virus’ binding and entry mechanisms guided by its tissue tropism and glycan engagement,” $2,500. She also an editorial board member for the Nature publication Scientific Reports and had three new publications this past month three as a co-author and one as a co-first author: Wilson WC, Davis AS*, Gaudreault NN, Faburay B, Trujillo JD, Shivanna V, Sunwoo SY, Balogh A, Endalew A, Ma W, Drolet B, Ruder MG, Morozov I, McVey DS, Richt JA. 2016. (*=co-first). Experimental Infection of Calves by Two Genetically Distinct Strains of Rift Valley Fever Virus. Viruses. 2016; 8(5).; Faburay B, Wilson WC, Gaudreault NN, Davis AS, Shivanna V, Bawa B, Sunwoo SY, Ma W, Drolet B, Morozov M, McVey DS, Richt JA. 2016. A Recombinant Rift Valley Fever Virus Glycoprotein Subunit Vaccine Confers Full Protection against Rift Valley Fever Challenge in Sheep. Scientific Reports. 2016; 6:27719.; and Kutty G, Davis AS, Ferreyra GA, Qiu J, Huang DW, Sassi M, Bishop L, Handley G, Sherman B, Lempicki R, Kovacs JA. b-glucans are Masked but Contribute to Pulmonary Inflammation During Pneumocystsis Pneumonia. J Infect Dis. 2016 (In Press).
Back row: Drs. Erik Perez, equine; Pierce Chan, small animal medicine & surgery; Megan Partyka, small animal medicine & surgery; Kyla Krissek, shelter medicine; and Katie Weatherall, equine. Front row: Drs. Lin-Yi Hsuan, small animal medicine & surgery; Lauren Pudenz, small animal medicine & surgery; Christina McCullough, livestock services; Lacey Robinson, livestock services; and Louden Wright, zoological medicine.
Deepti Pillai receives the University Support Staff Employee of the Year Award for the Department of Diagnostic Medicine/Pathobiology, presented by Dean Tammy Beckham and Department Head Dr. M.M. Chengappa.
Haixia Liu accepts the Unclassified Staff Employee of the Year Award from Dean Beckham and Dr. Chengappa.
The following employees were recognized for years of service.
Officials of the Center of Excellence for Emerging and Zoonotic Animal Diseases (CEEZAD) celebrated the opening of its new headquarters June 22 with an open house attended by stakeholders, collaborators, and Kansas State University officials.
Dr. Juergen Richt, Regents Distinguished Professor, Diagnostic Medicine and Pathology at Kansas State University and director of CEEZAD, welcomed the dignitaries at an evening reception held at the offices, which are in the KSU Office Park. The building, which is also home to the KSU Foundation, opened in the fall of 2015.
CEEZAD is a Department of Homeland Security Center of Excellence established in 2010 with a focus on the protection of the nation’s agricultural and public health sectors against high-consequence foreign animal, emerging and zoonotic disease threats. Although it has a broad mission, CEEZAD scientists concentrate their efforts in four principal areas:
Dr. Richt welcomed participants with a clear message that CEEZAD’s mission would be enhanced in its new headquarters. “As you take it in today, I’m sure you will agree with me that it is a fine, modern facility, fully appropriate for carrying forward the center’s mission of making America, and the world, safer,” he said.
He noted that CEEZAD has since its inception researched efforts to enhance biodefense capabilities via threat awareness, vulnerability assessments, surveillance and detection, as well as response and recovery. “We conduct research, develop technology and train a specialized workforce to help defend U.S. agricultural systems against agroterrorism and other catastrophic events caused by high-threat transboundary, emerging and zoonotic pathogens,” he said.
Among accomplishments cited by Dr. Richt to date:
In Dr. Richt’s closing remarks, he states “As we open and occupy these new offices, you can be assured that our efforts in all of these regards will continue and intensify.”
These efforts are wholly or in-part supported by the U. S. Department of Homeland Security under the Center of Excellence of Emerging and Zoonotic Animal Diseases Grant Award Number 2010-ST061-AG0001.
KSU Office of Research and Sponsored Programs (ORSP) University Small Research Grant (USRG). “Developing a computer model to improve pain treatment in dogs using existing data,” July 1, 2016 - June 30, 2017. $4,343. PI: Zhoumeng Lin.
Lee C, Comer J, Herndon C, Leung N, Pavlova A, Swift R, Tung C, Rowley CN, Amaro R, Chipot C, Wang Y, Gumbart JC. Simulation-based approaches for determining membrane permeability of small compounds. J. Chem. Inf. Model. 56 (4): 721–733, 2016.
Comer J, Aksimentiev A. DNA sequence-dependent ionic currents in ultra-small solid-state nanopores. Nanoscale 8 (18): 9600–9613, 2016.
Aryal S, Stigliano C, Key J, Ramirez M, Anderson J, Karmonik C, Fung S, Decuzzi P. Paramagnetic Gd3+ labeled red blood cells for magnetic resonance angiography. Biomaterials 98, 163-170, 2016.
Delong RK, Hurst MN, Aryal S, Inchun NK. Unique Boron Carbide Nanoparticle Nanobio Interface: Effects on Protein-RNA Interactions and 3-D Spheroid Metastatic Phenotype. Anticancer Research 36(5): 2097-103, 2016.
Geoffrey N. Manani, Ryan T. Spidle, Anagh Bhaumik, Kartik Ghosh, Raja Ram Pandey, Charles C. Chusuei, Robert Delong and Adam K Wanekaya. Novel aqueous fabrication and characterization of gold coated cobalt nanoparticles. Current Bionanotechnology 1(2): 95 – 101, 2016.
Lin Z, Vahl CI, Riviere JE. Human food safety implications of variation in food animal drug metabolism. Scientific Reports, 2016;6:27907.
Abstracts/ Poster Presentations:
Pitchaimania A, Nguyen TDT, Wang H, Bossmann SH, Aryal S. Gadolinium Infused Theranostic Liposomes for Anticancer Therapy. American Association of Pharmaceutical Scientists (AAPS) National Biotechnology Conference, Boston, Poster # M1017, 2016.
Thomas SE, Marroquin S , DeLong RK. Elucidating the dynamics of nanoparticle-protein interaction at a biomolecular level: structural and functional studies using firefly luciferase, B328 969.43 Cell Signaling: Proteins, Pathways and Mechanisms Session. American Physiology Society, EB. San Diego, April 4, 2016.
Ramani M, DeLong RK. Absorption mechanisms of poly I:C RNA onto zinc oxide Nanoparticles: Maximizing Payload”, C136, 823.4, Nanotechnology session, American Society for Biochemistry and Molecular Biology, EB. San Diego, April 4, 2016.
Ramani M, Dean JM, Hurst MN, Chandran P, Monteiro-Riviere NA, DeLong RK. Cobalt oxide nanoparticle mediated delivery of splice switching oligonucleotides (SSO) RNA. The 8th World Medical Nanotechnology Congress and Exposition. Dallas, June 9, 2016.
Comer J. "Implementing unusual force fields in NAMD". NAMD Developer Workshop, Chicago. May 27, 2016.
Comer J. "Simulations at the interface between biology and synthetic materials". Université de Lorraine, Nancy, France, June 15, 2016.
Dr. De Long was an invited speaker: “Characterizing the nanobio interface of bio-metal or bio-metal oxide nanoparticles: Impact on the function and delivery of proteins and RNA” and Co-Chair of Session at The 8th World Medical Nanotechnology Congress and Exposition. Dallas, June 9, 2016.
Several NICKS faculty and postdoctoral fellows presented their research findings at the 8th International Nanotoxicology Congress in Boston in June.
Dr. Yang Li (spotlight left) and Dr. Abhilash Sasidharan receive travel awardsat the 8th International Nanotoxicology Congress in Boston (see list below).
Dr. Ran Chen, Postdoctoral fellow of Dr. Jim Riviere received the Outstanding Poster Award on his research entitled “Biological surface adsorption index: environmental applications and parallel molecular dynamics simulation.”
Dr. Parwathy Chandran, Postdoctoral fellow of Dr. Nancy Monteiro-Riviere was selected for an oral presentation on “Role of physicochemical properties of gold nanoparticles on biocorona formation and cellular uptake profiles in endothelial cells.”
Dr. Abhilash Sasidharan, Postdoctoral fellow of Dr. Nancy Monteiro-Riviere received a Travel Award to attend the Congress based on his abstract “Understanding the impact of biocorona on the interaction of gold nanoparticles with human blood components."
Dr. Yang Li, Postdoctoral fellow of Dr. Nancy Monteiro-Riviere received a Travel Award to attend the Congress based on his abstract “Cellular uptake mechanisms of gold nanoparticles with three different coatings and protein corona effects on cell uptake in human keratinocytes.”
Dr. Kyoungju Choi, Research Assistant Professor in Dr Nancy Monteiro-Riviere’s laboratory gave a presentation on “In vitro assessment of size, surface chemistry and protein corona effects on hepatic uptake and toxicity of gold nanoparticles in human hepatic cells."
Dr. Zhoumeng Lin gave an oral presentation on “PBPK modeling of gold nanoparticles: a tool to extrapolate from animals to man.”
Dr. Jim Riviere organized and Chaired the “Physiological based pharmacokinetic modeling of nanomaterials” session and gave a presentation on the Physiological based pharmacokinetic modeling of nanomaterials: why is quantitation and anatomical /physiological reality so important?
Dr. Nancy Monteiro-Riviere served on the International Organization Advisory Board for the International Nanotoxicology Congress, the Abstract Review Committee, and served on the Panel Discussion Member for the Opening Ceremony and Chaired the Biomolecular Corona Session.
Oldenburg S, Hunt P, Hussain SM, Monteiro-Riviere NA. Searching for risk, finding value: unexpected developments from nanotoxicology/industry collaborations. The 8th International Nanotoxicology Congress, p. 377, #59, 2016.
Brown J, Monteiro-Riviere NA. Impact of the biomolecular corona on nanoparticle uptake and cellular response. The 8th International Nanotoxicology Congress. p. 28, 2016.
Beef Cattle Institute's Beef Scholars program provides opportunities for students, resources for beef industry
Beef Cattle Institute Beef Scholars from left: A.J. Cabanatuan, Sarah Jones, Paula Mendez, third-year veterinary student Carlee Wollard (spotlight), Amanda Kathrens, Jose Soto, doctoral student in pathobiology Allison McKiearnan (spotlight) and Kevin Manase.
Eight Kansas State University students from majors across campus are serving as the inaugural participants in the Beef Cattle Institute's Beef Scholars program this summer.
Baby Boy Bonanza
New Arrivals/Recent Departures
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