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College of Veterinary Medicine

Megan C. Niederwerder

megan

Assistant Professor

B.S. (2005), Northwest Missouri State University
D.V.M. (2009), Kansas State University
Ph.D. (2015), Kansas State University
Office: L-227 Mosier Hall
Phone: 785-532-4663
Email: mniederwerder@vet.k-state.edu

Teaching and Service

I serve as Course Coordinator and Instructor in the DMP822 Veterinary Virology course (3 credit hours) for veterinary students in the second year of the professional curriculum.  My lectures include viral diseases of swine, equine, avian and canine species.  My service role includes diagnostic test development for viral diseases and microbiome characterization. 

Research

My research primarily focuses on understanding how the microbiome plays a role in outcome following viral infection in swine as well as the role of feed in the introduction and transmission of swine viruses.  Research projects have included porcine reproductive and respiratory syndrome virus (PRRSV), porcine circovirus type 2 (PCV2), porcine epidemic diarrhea virus (PEDV), African swine fever virus (ASFV), classical swine fever virus (CSFV), and pseudorabies virus (PRV).    

Peer-Reviewed Publications (*Indicates corresponding author) 

  1. *Dee, S.A., F.V. Bauermann, M.C. Niederwerder, A. Singrey, T. Clement, M. de Lima, C. Long, G. Patterson, M.A. Sheahan, A.M.M. Stoian, V. Petrovan, C.K. Jones, J. De Jong, J. Ji, G.D. Spronk, L. Minion, J. Christopher-Hennings, J.J. Zimmerman, R.R.R. Rowland, E. Nelson, P. Sundberg, and D.G. Diel. 2018. Survival of viral pathogens in animal feed ingredients under transboundary shipment models. PLoS One. doi: 10.1371/journal.pone.0194509.
       
  2. *Niederwerder, M.C. and R.A. Hesse. 2018. Swine enteric coronavirus disease: A review of 4 years with porcine epidemic diarrhea virus and porcine deltacoronavirus in the United States and Canada. Transbound Emerg Dis. doi: 10.1111/tbed.12823.   

  3. Dunkelberger, J.R., N.V.L. Serão, Z. Weng, E.H. Waide, M.C. Niederwerder, M.A. Kerrigan, J.K. Lunney, R.R.R. Rowland, *J.C.M. Dekkers. 2017. Genomic regions associated with host response to porcine reproductive and respiratory syndrome vaccination and co-infection in nursery pigs. BMC Genomics. 18:865.

  4. Ober, R.A., J.B. Thissen, C.J. Jaing, A.G. Cino-Ozuna, R.R.R. Rowland, and *M.C. Niederwerder. 2017. Increased microbiome diversity at the time of infection is associated with improved growth rates of pigs after co-infection with porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus type 2 (PCV2). Vet Microbiol. 208: 203-211.

  5. *Niederwerder, M.C. 2017. Invited review. Role of the microbiome in swine respiratory disease. Vet Microbiol. 209: 97-106.

  6. Dunkelberger, J.R., N.V. Serão, M.C. Niederwerder, M.A. Kerrigan, J.K. Lunney, R.R. Rowland, and *J.C. Dekkers. 2017. Effect of a major quantitative trait locus for porcine reproductive and respiratory syndrome (PRRS) resistance on response to coinfection with PRRS virus and porcine circovirus type 2b (PCV2b) in commercial pigs, with or without prior vaccination for PRRS. J Anim Sci. 95(2): 584-598.

  7. *Niederwerder, M.C., and R.R.R. Rowland. 2017. Is there a risk for introducing porcine reproductive and respiratory syndrome virus (PRRSV) through the legal importation of pork? Food Environ Virol. 9(1): 1-13.

  8. *Niederwerder, M.C., J.C. Nietfeld, J. Bai, L. Peddireddi, B. Breazeale, J. Anderson, M.A. Kerrigan, B. An, R.D. Oberst, K. Crawford, K.M. Lager, D.M. Madson, R.R.R. Rowland, G.A. Anderson, and R.A. Hesse. 2016. Tissue localization, shedding, virus carriage, antibody response and aerosol transmission of Porcine epidemic diarrhea virus (PEDV) following inoculation of 4-week-old feeder pigs. J Vet Diagn Invest. 28(6): 671-678.

  9. *Niederwerder, M.C., C.J. Jaing, J.B. Thissen, A.G. Cino-Ozuna, K.S. McLoughlin, and R.R. Rowland. 2016. Microbiome associations in pigs with the best and worst clinical outcomes following co-infection with porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus type 2 (PCV2). Vet Microbiol. 188: 1-11.

  10. *Niederwerder, M.C., B. Bawa, N.V. Serão, B.R. Trible, M.A. Kerrigan, J.K. Lunney, J.C. Dekkers, and R.R. Rowland. 2015. Vaccination with a porcine reproductive and respiratory syndrome (PRRS) modified live virus vaccine followed by challenge with PRRS virus and porcine circovirus type 2 (PCV2) protects against PRRS but enhances PCV2 replication and pathogenesis compared to results for nonvaccinated cochallenged controls. Clin Vaccine Immunol. 22(12): 1244-54.

  11. *Jaing, C.J., J.B. Thissen, S.N. Gardner, K.S. McLoughlin, P.J. Hullinger, N.A. Monday, M.C. Niederwerder, and R.R. Rowland. 2015. Application of a pathogen microarray for the analysis of viruses and bacteria in clinical diagnostic samples from pigs. J Vet Diagn Invest. 27(3): 313-325.

  12. *Niederwerder, M.C., I.H. Stalis, G.A. Campbell, and K.A. Backues. 2013. Gastric pneumatosis with associated eosinophilic gastritis in four black and white ruffed lemurs (Varecia variegata variegata). J Zoo Wildl Med. 44(1): 79-86.

  13. *Niederwerder, M.C., S. Crochik, M.C. Rochat, and K.A. Backues. 2011. Clinical Challenge: Diskospondylitis of L6-L7 in a snow leopard cub (Uncia uncia). J Zoo Wildl Med. 42(4): 774-777.