1. K-State home
  2. »College of Veterinary Medicine
  3. »Education
  4. »Anatomy and Physiology
  5. »Faculty and Staff
  6. »Faculty
  7. »Philine Wangemann
  8. »Expertise

College of Veterinary Medicine

Philine Wangemann

Calcium Sparks and WavesExpertise

Calcium Sparks and Waves

Calcium sparks and waves are measured in the spiral modiolar artery of the gerbil. The spiral modiolar artery is an arteriole with an outer diameter of ~60 µm that supplies the cochlea of the inner ear. Calcium waves are slow events with times of half-decay of ~5 s and sparks are fast events with times of half-decay of ~20 ms.

Confocal imaging and line-scanning is used to measure the cytosolic Ca2+ concentration with enhanced image or time resolution (510 META, Carl Zeiss).

Movies from the lab

Vasoconstriction (avi)
Sparks and waves (avi)
Sparks (avi)

Papers from the lab

Scherer et al (2001) (pdf)
Scherer et al (2002) (pdf)
Herzog et al (2002) (pdf)