Calcium Sparks and Waves
Calcium sparks and waves are measured in the spiral modiolar artery of the gerbil. The spiral modiolar artery is an arteriole with an outer diameter of ~60 µm that supplies the cochlea of the inner ear. Calcium waves are slow events with times of half-decay of ~5 s and sparks are fast events with times of half-decay of ~20 ms.
Confocal imaging and line-scanning is used to measure the cytosolic Ca2+ concentration with enhanced image or time resolution (510 META, Carl Zeiss).