College of Veterinary Medicine, Kansas State University

Dr. Cathleen A. Hanlon, chanlon@vet.ksu.edu
Director, K-State Rabies Laboratory,
College of Veterinary Medicine,
Veterinary Diagnostic Laboratory

Program Schedule

Workshop Modules

Fundamental concepts
Biologics development, measures of potency and safety, and regulatory requirements
Measures of immunity in humans
Companion animal serology and management of livestock
Wildlife immunization and serology

Each module will consist of 3-5 short presentations and a panel discussion.

A summary document of guidelines and recommendations will be developed during the concluding session.

Workshop Modules – Detailed Schedule
Wednesday April 21, 2010

*Welcome to participants*
CST or GMT - 5.0		CET
8:00	· Dr William Brown, Livestock Commissioner of the State of Kansas · Mr Bruce Snead, Mayor of the City of Manhattan Kansas · Dr Ralph Richardson, Dean, Kansas State University College of Veterinary Medicine (video) · Dr Dan Getman, President, Kansas City Area Life Sciences Institute (video) · Dr Michael Cates, Director of the Masters of Public Health Program at K-State · Dr Beth Montelone, Interim Director of the Biosecurity Research Institute and Associate Dean of the College of Arts and Sciences	15:00
8:15	Rabies Immunology Pre/Avant-Workshop Quiz - all participants are asked to take 15 minutes to read and respond individually to the test questions. At the end of the program, we will ask you to take the test again to assess our learning objectives.	15:15
*Fundamental concepts*
8:30	Dr. Cathleen Hanlon, VMD, PhD, Dipl ACVPM Director, Kansas State University Rabies Laboratory, Manhattan, Kansas Evolution in Kansas towards excellence in quality practices and essential rabies laboratory methods	15:30
8:45	Dr Susan J Wong , PhD, Dipl ABMLI Director, Diagnostic Immunology Laboratory, Wadsworth Laboratories, NYSDOH, Albany, NY USA Evolution of Testing Platforms for Serodiagnosis and Proof of Immunity	15:45
9:30	Robin Levis, PhD United States Food and Drug Administration, Center for Biologics and Research, MD Regulatory Considerations Related to Biologics Used in Rabies Pre- and Post-Exposure Prophylaxis	16:30
10:15	Morning Break	17:15
10:30	Donna Gatewood, DVM, MS United States Department of Agriculture, Center for Veterinary Biologics, Ames IA Regulatory Requirements for Licensure of Rabies Vaccines in the United States	17:30
11:15	Ms. Chandra Gordon Quality Program Manager, Kansas State University Veterinary Diagnostic Laboratory, Manhattan, KS The Evolution of the Kansas State University Rabies Laboratory: >25 years in the making	18:15
12:00	Lunch Break	19:00
13:00	Susan Moore, MS, MT(ASCP)SBB Rabies Laboratory Manager, Kansas State University Rabies Laboratory, Manhattan, Kansas Standardizing rabies serology methods – Why, When, How?	20:00
13:45	Panel Discussion	20:45
*Aspects of human serology*
14:15	Dr. Alexander Wandeler Canadian Food Inspection Agency, ADRI, Centre of Expertise for Rabies, Ontario The WHO recommendation of 0.5 IU/ml as adequate or “protective”	21:15
14:30	Susan Moore, MS, MT(ASCP)SBB The Kansas State University Rabies Laboratory Identifying, understanding and controlling method variables and reporting of results - IU versus Titer	21:30
15:15	Afternoon Break	22:15
15:30	Michael Niezgoda, MS Centers for Disease Control and Prevention, Rabies Team, Atlanta, GA Indirect immunofluorescence (IFA) test for the detection of rabies IgG and IgM antibody in suspect human rabies cases	22:30
16:00	Dale Claassen, MS, PhD The Kansas State University Rabies Laboratory The inevitability of change: A Laboratory Investigation of autofluorescent slides and unstackable trays	23:00
16:30	Panel Discussion	23:30
17:00	Conclusion	24:00

Thursday April 22, 2010

*Pet Travel*
CST or GMT - 5.0		CET
8:00	Dr. Beverly Schmitt United States Department of Agriculture, National Veterinary Services Laboratory, Ames IA Vice President of the World Organisation for Animal Health, Scientific and Technical Committee The OIE Biological Standard Commission and its role in the development and updating OIE Standards	15:00
8:30	Dr. Cathleen Hanlon, VMD, PhD, Dipl ACVPM Director, Kansas State University Rabies Laboratory, Manhattan, Kansas Towards excellence in quality practices and essential rabies laboratory methods	15:30
9:15	Dan David, DVM, PhD Head, Rabies Laboratory, Pathology Division, Kimron Veterinary Institute, Bet Dagan, Israel Rabies in a two vaccinated dogs in Israel, 2010	22:30
9:45	Morning Break	16:45
10:00	Dr Lorraine McElhinney Veterinary Laboratories Agency, Weybridge, United Kingdom Overview of testing at VLA: FAVN, ELISA and new technologies	17:00
10:45	Dr Conrad Freuling Friedrich Loeffler Institute, Federal Research Institute for Animal Health, Wusterhausen, Germany Evaluating the use of an ELISA in the frame of marketing authorisation in Germany	17:45
11:30	Susan Moore, Dale Claassen and Lorraine McElhinney Kansas State Rabies Laboratory and Veterinary Laboratories Agency Comparative study of FAVN and ELISA methods applied at two different laboratories on the same samples	18:30
12:00	Lunch Break	19:00
*Wildlife Serology*
13:00	Dr. Adrian Vos IDT Biologika GmgH, Dessau-Rosslau, Germany Efficacy studies of oral rabies vaccines and the 0.5 IU/ml threshold	20:00
13:20	Michael Niezgoda, MS Centers for Disease Control and Prevention, Rabies Team, Atlanta, GA Wildlife serology and the effect of lowering the “cut-off” levels	20:20
13:40	Cathleen Hanlon, VMD, PhD, Dipl ACVPM Kansas State University Rabies Laboratory, Manhattan Kansas Rabies challenge results of raccoons from the field	20:40
14:00	Dr. Conrad Freuling Friedrich Loeffler Institute, Federal Research Institute for Animal Health, Wusterhausen, Germany Serological monitoring of ORV campaigns in wildlife – a European perspective	21:00
14:20	Dr. Christine Fehlner-Gardiner Canadian Food Inspection Agency, ADRI, Centre of Expertise for Rabies, Ontario Development and validation of a competitive ELISA for wildlife rabies serology - Lessons learned	21:20
14:40	Panel Discussion	21:40
14:55	Rabies Immunology Post/Après-Workshop Quiz - Please re-take the test offered at the beginning of the workshop.	21:55
15:00	Conclusion of the Webcast - On-Site participants work on a summary.	22:00