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Kansas State University

 

Lalitha Peddireddi

 



Lalitha Peddireddi
BVSc & AH (DVM equivalent) 2001, ANGR Agricultural University, Hyderabad, India
MS 2004, Purdue University
PhD 2009, Kansas State University

Research Assistant Professor, Molecular Diagnostics
Veterinary Diagnostic Laboratory
Office: 157 Research Park
Phone: (785) 532 4425
Fax: 785-532-4481
Email: lalitha@vet.k-state.edu


 

 

 

 

Research

Molecular Diagnostic test development and validation:
 
My research focus is to develop and validate PCR-based molecular diagnostic assays for use in routine diagnostic setting to detect veterinary pathogens and those of zoonotic importance. My special interest lies in development of molecular-based detection assays to identify vector-borne veterinary pathogens. In addition, I am highly interested in developing organ system specific, multiplex PCR panels targeted to common pathogens capable of causing diseases in a specific organ system.

Collaborative research:

I participate in clinical and collaborative research activities involving pathologists and clinicians at Kansas State University to identify the cause of an unknown illness using molecular approaches with a goal of translating basic molecular knowledge to the actual practice of clinical medicine.

In addition, I work on molecular diagnostic projects collaborated with industry partners. These projects are primarily intended to develop and validate real-time RT-PCR based assays to diagnose a variety of veterinary pathogens including those of zoonotic potential.
 

Service

I participate and oversee daily diagnostic activities at Kansas State Veterinary Molecular Diagnostic Laboratory (KSMDL). I also involve in client consultation involving PCR-based detection assays.

Selected Publications:

Lee Effinger, Lalitha Peddireddi, Marilyn Simunich, Richard Oberst, Catherine O’Connell, Ivan Leyva-Baca. 2013. Pooling of Cultured Samples and Comparison of Multi-State Laboratory Workflows with the MagMAX™ Sample Preparation System and VetMAX™ qPCR Reagents for Detection of Tritrichomonas foetus Colonized Bulls. JVDI (in review)

Nickell JS, White BJ, Larson RL, Renter DR, Oberst R, Hesse R, Pedireddi L, Anderson G. 2011. Onset and Duration of Transient Infections Among Antibody- Diverse Beef Calves Exposed to a Bovine Viral Diarrhea Virus Persistently Infected Calf.  J International Journal for Applied Research in Veterinary Medicine. Vol 9, No.1.

Bonto Faburay, Huitao Liu, Lalitha Peddireddi and Roman Ganta. 2011. Isolation and characterization of Ehrlichia chaffeensis RNA polymerase and its use in evaluating p28 outer membrane protein gene promoters. BMC Microbiology, 11:83

Peddireddi, L., Cheng, C. and R.R. Ganta. 2009.  Promoter analysis of macrophage- and tick cell-specific differentially expressed Ehrlichia chaffeensis p28-Omp genes.  BMC Microbiology, 9: 19.

Roman Reddy Ganta, Lalitha Peddireddi, Gwi-Moon Seo, Sarah Elizabeth DeDonder, Chuanmin Cheng, and Stephen Keith Chapes.  2009. Molecular characterization of Ehrlichia interactions with tick cells and macrophages. Review. Frontiers In Bioscinces. 14: 3259-73.

Lalitha Peddireddi. 2009. Transcriptional analysis and promoter characterization of two differentially expressed outer membrane protein genes of Ehrlichia chaffeensis. K-state Research Exchange.

Ganta, R.R., Cheng, C., Miller, E.C., McGuire, B.L., Peddireddi, L., Sirigireddy, K.R. and Chapes, S.K. 2007. Differential Clearance and Immune Responses to Tick Cell-Derived versus Macrophage Culture- Derived Ehrlichia chaffeensis in Mice. Infection and Immunity, 75:135-145.

Singu, V., Peddireddi, L., Sirigireddy, K.R., Cheng, C., Munderloh, U. and Ganta, R.R. 2006. Unique Macrophage and Tick Cell-specific Protein Expression from the p28/p30-Omp Multigene Locus in Ehrlichia Species. Cellular Microbiology, 8 (9), 1475-1487.

Saddoris, K.L., Peddireddi, L., Trapp, S.A., Richert, B.T., Harmon, B. and Radcliffe, J.S. 2005. The Effects of Supplemental Pantothenic Acid in Grow-Finish Pig Diets on Growth Performance and Carcass Composition.The Professional Animal Scientist. (21): 443-448.

Walsh, M.C., Peddireddi, L. and Radcliffe, J.S. 2004. Acidification of Nursery Diets : Acidification of Nursery Diets and the Role of Diet Buffering Capacity. Porknet newsletter, Tuesday, September 14 - Daily Update.

Peddireddi, L., A.L. Yager, K.L. Saddoris, L.M. Wilson, M.C. Walsh, D.M. Sholly, R.B. Hinson, B.T. Richert, and J.S. Radcliffe. 2004. The effects of dietary calcium source and level on growth performance. J. Anim. Sci. 82 (Suppl. 2): 45.

Yager, A., L. Wilson, K. Saddoris, L. Peddireddi, R. Hinson, M. Walsh, D. Sholly, B. Richert, A. Schinckel, and J.S. Radcliffe. 2004. Effects of increasing TSAA:Lys on performance and carcass characteristics of gilts fed a ractopamine step-up program. J. Anim. Sci. 82 (Suppl. 1): 99.

Peddireddi, L. and Radcliffe, J.S. 2003. The effects of dietary calcium level and citric acid supplementation on growth performance and gastrointestinal pH in chicks. J Anim. Sci Vol. (81), Supplement 2.

Radcliffe, J.S., Richert, B.T., Peddireddi, L., and Trapp, S.A.. 2003. Effects of Supplemental Pantothenic Acid During All or Part of the Grow-Finish Period on Growth Performance and Carcass Composition. Swine Research Reports. Pp 108-114.

Hinson, R., Hill, B., Walsh, M., Sholly, D., Kelly, D., Cobb, M., Peddireddi, L., Radcliffe, S.,  Sutton, A., Schinckel, A. and Richert. B. 2003. Effect of Feeding a Reduced Crude Protein and Reduced Phosphorus Diet on Growth Performance and Carcass Characteristics in Grow-Finish Swine. Swine Research Reports. Pp 115-124.

Hinson, R., Walsh, M., Sholly, D.,  Kelly, D., Cobb, M., Peddireddi, L. Radcliffe, S., Sutton, A. 2003.   The effect of Feeding a Low Nutrient Excretion Diet on Growth Performance and Carcass Characteristics of Nursery, Grower, and Finisher Pigs Swine Research Reports. Pp 125-134.