Postdoctoral Research Associate 2008-2013, Kansas State University
Ph.D. 2008, Institute of Microbial Technology, CSIR- Chandigarh, India
M.Sc. 2002, Rajabazar Science College, University of Calcutta, Kolkata, India
B.Sc. 2000, Presidency University, Kolkata, India
Research Assistant Professor, Microbial Ecology
Our laboratory addresses the key issues related to public and environmental health. My expertise centers on studying ecology of antibiotic resistance traits and food-borne pathogens in the gut of mammals, birds, insects, and the environment.
Development of bacterial resistance to important classes of antibiotics and the resulting loss of drug effectiveness for antimicrobial therapies pose a serious public health threat. We primarily study the ecology of zoonotic and food-borne pathogens in agricultural, veterinary, and urban environments with special emphasis on antibiotic resistant strains of enterococci and Shiga-toxigenic Escherichia coli (O157 and non-O157). Using molecular genotyping and diagnostics, we aim to understand how insects serve as a reservoir and play a role in the transmission of pathogenic/antibiotic resistant strains within and outside cattle feedlots, swine, and poultry farms. Pest management recommendation based on our results will strengthen pre-harvest food safety strategies.
Considering the close physical contact between the companion animals, their owners, and veterinary personnel, we conduct research to better understand the ecology of multi-drug resistant strains of enterococci in the veterinary hospital environment and in the gut of healthy and sick small pet animals.
Leishmaniasis is recognized as a fatal zoonotic disease in many parts of the world and sand flies are the invertebrate vector for the Leishmania parasites. We are deciphering the role of the sand fly gut microbiome in the vector competence, which will potentially lead to paratransgenic manipulation of flies in order to curb the human outbreaks.
I am also interested in bacterial systematics including identification of novel taxa using polyphasic taxonomic approach. Responsibilities other than research involve lab management, grant preparation, scientific presentations, training and supervising undergraduate and graduate students and visiting scholars.
Ghosh A., Borst L., Stauffer S. H., Suyemoto M., Moisan P., Zurek L., and Gookin J. L. 2013. Mortality in kittens is associated with a shift in ileum mucosa-associated enterococci from E. hirae to biofilm-forming E. faecalis and adherent E. coli. J. Clin. Microbiol.(In Review)
Frolkova P., Svec P., Ghosh A., Zurek L., Oravcova V., Radimersky T., Bohus M., Bardon J., and Literak I. 2013. Species distribution and genotypic characterization of Enterococcus isolates from coraciiform birds.Antonie van Leeuwenhoek(In Review)
Oravcova V., Ghosh A., Zurek L., Bardon J., Guenther S., Cizek A., and Literak I. 2013. Vancomycin resistant enterococci in rooks (Corvus frugilegus) wintering throughout Europe. Environ. Microbiol.15:548-556.
Ghosh A., Brown C. E., KuKanich K., and Zurek L. 2012. Resident cats in small animal veterinary hospitals carry multi-drug resistant enterococci and are likely involved in cross-contamination of the hospital environment. Front. Microbiol. 3:62.
KuKanich K., Ghosh A., Skarbek J., Lothamer K., and Zurek L. 2012. Surveillance of bacterial contamination in small animal veterinary hospitals with special focus on antimicrobial resistance and virulence traits of enterococci. J. Am. Vet. Med. Assoc. 240:437-445.
Ghosh A., Dowd S. E., and Zurek L. 2011. Dogs leaving the ICU carry a very large multi-drug resistant enterococcal population with capacity for biofilm formation and horizontal gene transfer. PLoS ONE 6:e22451.
Ahmad A., Ghosh A., Schal C., and Zurek L. 2011. Insects in confined swine operations carry a large antibiotic resistant and potentially virulent enterococcal community. BMC Microbiol. 11:23. (Press release)
Macovei L., Ghosh A., Thomas V., Hancock L., Mahmood S., and Zurek L. 2009. Enterococcus faecalis with the gelatinase phenotype regulated by the fsr-operon and with biofilmforming capacity are common in the agricultural environment. Environ. Microbiol. 11:1540-1547.
Environmental Microbiology and Bacterial Systematics
Frolkova P., Svec P., Sedlacek I., Maslanova I., Cernohlavkova J., Ghosh A., Zurek L., Radimersky T., and Literak I. 2013. Enterococcus alcedinis sp. nov., isolated from common kingfisher (Alcedo atthis). Int. J. Syst. Evol. Microbiol.DOI:10.1099/ijs.0.049833-0
Frolkova P., Ghosh A., Svec P., Zurek L., and Literak I. 2012. Use of the manganese-dependent superoxide dismutase gene (sodA) for rapid identification of recently described enterococcal species. Folia Microbiologica 57:439-442.
Pandey J., Sharma N. K., Khan F., Ghosh A., Oakeshott J. G., Jain R. K., and Pandey G. 2012. Chemotaxis of Burkholderia sp. strain SJ98 towards chloronitroaromatic compounds that it can metabolise. BMC Microbiol. 12:19.
Ghosh A., Khurana M., Chauhan A., Takeo M., Chakraborti A. K., and Jain R. K. 2010. Degradation of 4-nitrophenol, 2-chloro-4-nitrophenol, and 2,4-dinitrophenol by Rhodococcus imtechensis strain RKJ300. Environ. Sci. Technol. 44:1069-1077.
Manickam N., Ghosh A., Jain R. K., and Mayilraj S. 2008. Description of a novel indole oxidizing bacterium Pseudomonas indoloxydans sp. nov., isolated from a pesticide contaminated site. Syst. Appl. Microbiol. 31:101-107.
Ghosh A., Goyal A., and Jain R. K. 2007. Study of methanol-induced phenotypic changes in a novel strain of Acinetobacter lwoffii. Arch. Microbiol. 188:533-539.
Ghosh A., Bhardwaj M., Satyanarayana T., Khurana M., Mayilraj S., and Jain R. K. 2007. Bacillus lehensis sp. nov. an alkalitolerant bacterium isolated from soil of Leh, India. Int. J. Syst. Evol. Microbiol. 57:238-242.
Tiwary B. N., Prasad B., Ghosh A., Kumar S., and Jain R. K. 2007. Characterization of two novel biovar of Agrobacterium tumefaciens isolated from root nodules of Vicia faba. Curr. Microbiol. 55:328-333.
Ghosh A., Paul D., Prakash D., Mayilraj S., and Jain R. K. 2006. Rhodococcus imtechensis sp. nov. a nitrophenol-degrading actinomycete. Int. J. Syst. Evol. Microbiol. 56:1965-1969.
Chandra R., Ghosh A., Jain R. K., and Singh S. 2006. Isolation and characterization of two potential pentachlorophenol degrading aerobic bacteria from pulp paper mill effluent sludge. J. Gen. Appl. Microbiol.52:125-130.