Faculty

 

 

 

 

 

David C. Poole

PhD, UCLA, 1986
DSc, Liverpool John Moores University, 2000

Phone (785) 532-4529  
e-mail poole@vet.k-state.edu

 

 

 

 

 

 

Research Interests:

David Poole is recognized internationally for his contributions to the fields of pulmonary gas exchange and skeletal muscle structure/function relationships. He has published over 100 peer reviewed papers in journals such as Circulation Research, Journal of Clinical Investigation, American Journal of Physiology and the Journal of Applied Physiology. Dr. Poole contributes invited chapters to major textbooks and presents his work before National and international scientific audiences on a regular basis. Since 1986, Dr. Poole has been awarded over 4 million dollars in funding and currently is examining the relationships between skeletal muscle structure and oxygen delivery at the microcirculatory level. This approach is anticipated to provide unique insights into the functional abnormalities which are associated with major disease conditions such as emphysema, diabetes and chronic heart failure.

Dr. Poole's laboratory is currently funded by grants from the National Institutes of Health and encourages a vibrant scientific atmosphere which stimulates productive interactions among faculty and students. Foremost among his collaborators at K-State, Dr. Poole wishes to acknowledge the significant contributions of Dr. Thomas J. Barstow, Dr. Timothy I. Musch, Dr. Howard H. Erickson, Dr. M. Roger Fedde, Dr. Casey A. Kindig and Dr. Brad J. Behnke.

In collaboration with Professor Andrew M. Jones of Manchester Metropolitan University in England, Dr. Poole has recently published a textbook entitled: "Oxygen Uptake Kinetics in Sport, Exercise and Medicine." This book is published by Routledge, London and New York, 2005, ISBN #-0-415-30560-8 (hardback) and 0-415-30561-6 (softback).

Selected Publications:

Padilla, D.J., P. McDonough, B.J. Behnke, Y. Kano, K.S. Hageman, T.I. Musch, D.C. Poole. Effects of Type II diabetes on muscle microvascular oxygen pressures. Resp. Physiol. Neurobiol. 156:187-195, 2007.

Hahn, S.A., L.F. Ferreira, J.B. Williams, K.P. Jansson, B. J. Behnke, T.I. Musch, D.C. Poole. Downhill treadmill running trains the rat spinotrapezius muscle. J. Appl. Physiol. 102:412-416, 2007.

McDonough, P., B.J. Behnke, D.J. Padilla, T.I. Musch, D.C. Poole. Control of microvascular oxygen pressures during recovery in rat fast-twitch muscle of differing oxidative capacity. Exp. Physiol. 92:731-8, 2007.

Behnke, B.J., M.D. Delp, T.I. Musch, D.C. Poole. Aging potentiates the effect of congestive heart failure on muscle microvascular oxygenation. J. Appl. Physiol. 103:1757-63, 2007.

Koga, S., D.C. Poole, L.F. Ferreira, B.J. Whipp, N. Kondo, T. Saitoh, E. Ohmae, T.J. Barstow. Spatial heterogeneity of quadriceps muscle deoxygenation kinetics during cycle exercise. J. Appl. Physiol. 103:2049-56, 2007.

Epp, T.S., H.H. Erickson, J. Woodworth, D.C. Poole. Effects of oral L-carnitine supplementation in racing Greyhounds. Equine Comp. Exerc. Physiol. 4: 141-148, 2007.

Poole, D.C., D.P. Wilkerson, A.M. Jones. Validity of criteria for establishing maximal O2 uptake during ramp exercise. Eur. J. Appl. Physiol. 102(4):403-10, 2008.

Jones, A.M., D.P. Wilkerson, F. DiMenna, J. Fulford, D.C. Poole. Validation of the ‘critical power’ concept for human exercise using 31P magnetic resonance spectroscopy. Am. J. Physiol. 294: R585-93, 2008.

Mattson, J.P., D.C. Poole, S.A. Hahn, T.I. Musch, R.T. Hinkle, R.J. Isfort. Maximal force is unaffected by emphysema-induced atrophy in extensor digitorium longus. Resp. Physiol. Neurobiol. 161: 119-124, 2008.

Herspring, K.F., S.W. Copp, L.F. Ferreira, B. Snyder, D.C. Poole, T.I. Musch. Effects of antioxidants on contracting spinotrapezius muscle force production and oxygen consumption in aged rats. J. Appl. Physiol. 105: 1889-1896, 2008.

Epp, T.S., K.L. Edwards, D.C. Poole, H.H. Erickson. Effects of conjugated estrogens and aminocaproic acid upon exercise-induced pulmonary hemorrhage. Comp. Exerc. Physiol. 5: 95-103, 2008.

Copp, S.W., L.F. Ferreira, K.F. Herspring, T.I. Musch, D.C. Poole. The effects of aging on capillary hemodynamics in contracting rat spinotrapezius muscle. Microvasc. Res. 2009, In press.

Copp, S.W., Davis R.T., Poole, D.C., Musch, T.I. Reproducibility of endurance capacity and VO2peak in male Sprague-Dawley rats. J. Appl. Physiol. 2009, In press.