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Kansas State University

Cellular Biophysics Lab

 

Gene Expression

Graph showing Knockdown of Gene Expression by RNA interference using siRNA

 

Semicircular canal epithelium was incubated with dexamethasone in the presence of either a non-silencing siRNA or siRNA specific for the apical epithelial sodium channel alpha subunit (α-ENaC). Transepithelial Na current was reduced by siRNA for α-ENaC.