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Kansas State University

Faculty

Faqir Muhammad

 

 

 

Dr. Faqir Muhammad

PhD, Comparative Biomedical Sciences, North Carolina State University, USA, 2004
MSc (Hons.), Vet. Pharmacology, University of Agriculture Faisalabad, Pakistan, 1997
DVM, University of Agriculture Faisalabad, Pakistan, 1995

 

Research Assistant Professor
Phone: 785-532-4380
Email: faqirm@vet.k-state.edu

 

 

Research Interests:

Quantitative Structure Activity Relationship (QSAR) analysis of different xenobiotics such as drugs, heavy metals, pesticides and hydrocarbons in different occupational scenarios for residue predictions in risk assessment. Dermal absorption kinetics and irritation studies of toxicants in invitro and invivo models to screen the chemicals for their safety. Pharmacokinetics of drugs and health protective effects of plant extracts against induced toxicological insults in animal models. Future research interests are population pharmacokinetics, PK-PD modeling and tissue distribution studies of xenobiotics/nanoparticles using invitro and invivo perfused tissues. I am interested in understanding the interactions of nanoparticles with protein corona in bio systems.

 

Selected Publications:

Muhammad, F.,  Awais, M,M., Akhtar, M., Anwar, M.I. (2013). Quantitative Structure activity relationship and risk analysis of some pesticides in the goat milk. Iranian Journal of Environmental Health Sciences and Engineering. 10:4, 1-5.

I. Javed, B. Aslam, F. Muhammad, M. Z. Khan, Z. U. Rahman, M. Ahmed, T. Khaliq and M. K. Saleemi, (2013). Heavy metal residues in goat meat during winter and summer seasons. Indo-American Journal of Pharmaceutical Research, 3(12):1501-1508.

Waheed, M., Muhammad, F., Javed, I., Akhtar, M., Saleemi, M.K. , Khaliq, T.,  Awais, M.M., and Anwar, M.A. (2013). Dermato-protective effects of some plant extracts (genus Ficus) against experimentally induced toxicological insults in rabbits.  Toxicology and Industrial Health. DOI: 10.1177/0748233713483190, first published on April 15, 2013.

N. Hashmi, F. Muhammad, I. Javed, J. A. Khan, M. Z. Khan, T. Khaliq and B. Aslam, (2013). Nephroprotective Effects of Ficus religiosa Linn (Peepal Plant) Stem Bark against Isoniazid and Rifampicin Induced nephrotoxicity in Albino Rabbits. Pakistan Veterinary Journal, 33 (3): 330-334.

Muhammad, F., and Riviere, J.E. (2012). Dermal Toxicity. In: Veterinary Toxicology: Basic and Clinical Principles, editor, Remesh Gupta. Elsevier Inc., Oxford: Academic Press, pages 337-350.

Muhammad, F.,  Javed, I., Akhtar, M., Rahman, Z.A.,  Awais, M.M., Saleemi, M.K., and  Anwar, M.I. (2012). Quantitative Structure activity relationship and risk analysis of some pesticides in the milk of cattle in Faisalabad-Pakistan. Pakistan Vet. J, 32(4):589-592.

Hussain, R., Mahmood, F., Khan, M.Z., Khan, A., Muhammad, F. (2011). Pathological and genotoxic effects of atrazine in male Japanese quail (Coturnix japonica). Ecotoxicology, 20: 1-8.

Shahzadi, A., I. Javed, B. Aslam, F. Muhammad, M.R. Asi, M. Y. Ashraf, Z. U. Rehman, and M.Z. Khan. (2011). Therapeutic effect of ciprofloxacin on the pharmacokinetics of carbamazepine in healthy male volunteers. Pakistan Journal of Pharmaceutical Sciences, 24: 63-68.

Muhammad, F., Haider, H., Rahman, Z.U., Javed, I., Khan, M.Z., Akhtar, M., Zafar, M., Anwar, M.I. (2010). Dermatotoxic effects of orally administered ciprofloxacin in sweating and non-sweating animal models. Cutaneous and Ocular Toxicology, 29 (4): 254-260.

Muhammad,F., Akhtar, M., Rahman, Z.U., Farooq, H.U., Khaliq, T., Anwar, M.I. (2010). Multi-residue determination of pesticides in the meat of cattle in Faisalabad-Pakistan. Egyptian Academic Journal of Biological Sciences F. Toxicology and Pest Control, 2 (2): 19-28.

Muhammad, F., Akhtar, M., Javed, I., Rahman, Z.U., Jan, I., Anwar, M.I., Hayat, S. (2009). Quantitative Structure Activity Relationship and Risk Analysis of Some Heavy Metal Residues in the Milk of Cattle and Goat. Toxicology and Industrial Health 25: 177-181.

Javed, I., Jan, I., Muhammad, F., Rahman, Z.U., Khan, M.Z., Aslam, B., Sultan, J. (2009). Heavy metal residues in the milk of cattle and goats during winter season. Bulletin of Environmental Contamination and Toxicology 82: 616-620.

Muhammad, F., Akhtar, M., Anwar, M.I., Arshad, M.J. (2009). Effect of induced pyrexia on the disposition kinetics of ciprofloxacin in dogs. Veterinary Research Communication 33: 971-977.

Javed, I., Iqbal, Z., Rahman, Z.U., Zargham, M. K., Muhammad, F., Aslam, B., Sandhu, M. A., and Sultan, J. I. (2009). Disposition kinetics and optimal dosage of ciprofloxacin in healthy domestic ruminant species. Acta veterinaria brno, 78, 155-162.

Javed, I., Iqbal, Z., Rahman, Z.U., Khan, M.Z., Muhammad, F., Khan, F.H., Sultan, J.I. (2009). Renal handling of ciprofloxacin in domestic ruminant species. Turkish Journal of Veterinary and Animals Sciences, 33(4): 303-310.

Muhammad, F., Riaz, A., Akhtar, M., Anwar, M.I., Mahmood, F., Javed, I., Khaliq, T., Rahman, Z.U., Khan, F.H., and Bashir, S. (2008). Estimation of Atrazine in the Stratum Corneum and its Toxic Effects in skin Following Topical Application to Rabbits. Toxicology Mechanisms and Methods, 18: (9) 697-703.

Muhammad, F., and Riviere, J.E. (2007). Dermal Toxicity. In: Veterinary Toxicology: Basic and Clinical Principles, editor, Remesh Gupta. Elsevier Inc., San Diego, California, U.S.A. pages 263-277.

Muhammad, F., and Riviere, J.E. (2006). In vivo models. In: Dermal absorption models in toxicology and pharmacology, editor, Jim. E. Riviere. CRC Taylor and Francis publishing’s, Florida, USA. Pages 49-70.

Muhammad, F., Monteiro-Riviere, N.A., and Riviere, J.E. (2005). Comparative in vivo toxicity of topical JP-8 jet Fuel and its individual hydrocarbon components: Identification of tridecane and tetradecane as key constituents responsible for dermal irritation. Toxicologic Pathology. 33: 258-266.   

Muhammad, F., Monteiro-Riviere, N.A., Baynes, R.E., and Riviere, J.E. (2005). Effect of in vivo jet fuel exposure on subsequent in vitro dermal absorption of individual aromatic and aliphatic hydrocarbon fuel constituents. Journal of Toxicology and Environmental Health A. May 14;68(9):719-37.

Muhammad, F., Brooks, J.D., and Riviere, J.E. (2004). Comparative mixture effects of JP-8 (100) additives on the dermal absorption and disposition of jet fuel hydrocarbons in different membrane model systems. Toxicology Letters 150, 351-365.

Muhammad, F., Baynes, R.E., Monteiro-Riviere, N.A., Xia, X.R., and Riviere, J.E. (2004). Dose related absorption of JP-8 jet fuel hydrocarbons through porcine skin with quantitative structure permeability relationship analysis. Toxicology Mechanisms and Methods 14, 159-166.