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Kansas State University

The Rudy Clarenburg Lecture Series


Dr. Rudy Clarenburg

The Rudy Clarenburg Lecture Series was established in 1996 to honor the late Rudolf Clarenburg, Professor of Anatomy and Physiology. The Lecture Series brings nationally and internationally acclaimed scientists to Kansas State University to discuss their research interests with students and faculty throughout the University.

Dr. Rudolf Clarenburg joined the Department of Anatomy and Physiology in October, 1966. He received his Doctor of Sciences in 1965 from Netherlands State University, Utrecht, Holland. Dr. Clarenburg was a Research Assistant/Associate in the Department of Physiology, University of California, Berkeley from 1959 to 1966. At K-State he taught courses in physiological chemistry, intermediary metabolism and veterinary physiology. In 1983 Dr. Clarenburg received the Norden Distinguished Teacher award “for distinguished teaching in the field of veterinary medicine.”

The Dr. Rudolf Clarenburg Lectureship is made possible by the generous support received from Mrs. Margalith Clarenburg and her family. Mrs. Clarenburg passed away on April 10, 2002, following a long battle with cancer. She is deeply missed by her family and friends, but her legacy and support for the Clarenburg Lecture Series will continue for many years to come.

The current lecture series features:

William B. Guggino, PhD
The Johns Hopkins University

Dr. Guggino’s lecture will be on April 3, 2007 at 4:00 p.m.:

“Macromolecular Complexes Directing the Trafficking of CFTR from the Golgi to the Plasma Membrane”

The seminar will be held in the Practice Management Center, Trotter Hall, College of Veterinary Medicine. Refreshments will be served at 3:30 p.m.

Dr. William B. Guggino, PhD

Dr. Guggino received his Ph.D. in 1978 from the University of North Carolina-Chapel Hill. His research interests include cystic fibrosis, polycystic kidney disease, gene therapy, epithelial cell biology, protein-protein interactions, ion channels, and protein localization. Dr. Guggino is Director of Physiology and also Director of the Cystic Fibrosis Research Development Center at Johns Hopkins. Dr. Guggino’s work on cystic fibrosis was recognized when he won the prestigious Doris F. Tulcin Cystic Fibrosis Research Award.

Dr. Guggino’s laboratory is involved in understanding the biology of cystic fibrosis and seeks to identify methods to treat or prevent the disease. Studies in his laboratory focus on understanding the molecular structure of the protein that is mutated to cause cystic fibrosis and to determine how this protein affects cellular function by its interaction with other proteins and by its function as an ion channel. His laboratory and the Cystic Fibrosis Research Center, are actively involved in testing and developing vectors that are used in human and animal gene therapy trials. Research is also being conducted to identify specific defects in anion channel regulation in cystic fibrosis patients.

In 1992, Dr. Guggino, along with Dr. Peter Agre, authored a seminal paper in Science, which detailed the discovery of the very first water-channel protein.

For more information about Dr. Guggino, please visit his webpage at
We are grateful that Dr. Guggino will present The Dr. Rudolf Clarenburg Lectureship in the College of Veterinary Medicine at Kansas State University. We hope that you will attend his lecture.

Former Clarenburg Lecturers

2006 Dr. Mark A. Knepper
2006 Dr. Avril Somlyo
2004 Dr. Jim Riviere
2003 Dr. Jeanne M. Nerbonne
2002 Dr. Michael Welsh
2002 Dr. Gerald DiBona
2001 Dr. George A. Brooks
1999 Dr. Arthur "Buzz" Brown
1998 Dr. Clara Franzini-Armstrong
1998 Dr. Gordon Mitchell
1997 Dr. Kim Johnson
1997 Dr. Larry Sinoway