Arthur M. Brown
Vice President for Research
The Rammelkamp Center for Education and Research
MetroHealth Medical Center
2500 MetroHealth Drive
Cleveland, OH 44109-1998
||University of Manitoba, Faculty of Medicine, Winnipeg,
||University of London, London, England
|1995||MA (Oxon., Hon.)||University of Oxford Oxford, England|
Life Insurance Medical Research Fellow, Department of Physiology, Middlesex Hospital Medical School, London, England, 1961-1964
Research Fellow, Cardiovascular Research Institute, University of California Medical Center, San Francisco, CA, 1964-1966
Established Investigator of the American Heart Association, 1967-1972
Josiah Macy Fellow, 1982-1983
Javits Neuroscience Investigator Award, 1978-1984
Alexander von Humboldt Fellow, FRG, 1985-present
The First Annual Daniel A. Nachshen Memorial Lecturer, University of Maryland, 1988
The Harry B. van Dyke Award for Excellence in Medical Research (Pharmacology), Columbia University College of Physicians and Surgeons, 1989
American Physiological Society Walter B. Cannon Lecturer, 1990
Trinity Fellow, New College, Oxford, 1990 (elected)
Robert M. Berne Series in Cardiovascular Sciences Lecturer, 1992
Recipient of American Heart Association Basic Research Prize, 1992
Recipient of the 1993-1994 Louis and Artur Lucian Award for Research in Circulatory Diseases
First Robert M. Berne Distinguished Lecturer of the American Physiological Society Cardiovascular Section
Newton-Abraham Visiting Professor in Medical, Biological and Chemical Sciences for 1995-1996 academic year, University of Oxford, England (elected)
Articles in Journals:
Accili, E.A., Kuryshev, Y.A., Wible, B.A. and Brown, A.M. Separable effects of human KvB1.2 and C-termini on inactivation and expression of human Kv1.4. J. Physiology (1998), 512.2, pp.325-336.
Priori, S., Schwartz, P.J., Napolitano, C., Bianchi, L., Takacs-Dennis, A., De Fusco, M., Brown, A.M., and Casari, G. A recessive variant of the Romano-Ward Long QT syndrome. Circ. 97:2420-2425, 1998.
Dumaine, R., Roy, M-L., and Brown, A.M. Blockade of HERG and Kv1.5 by Ketoconazle1. J. Pharmacol. Exp. Ther. 286:727-735, 1998.
Schwalbe, R.A., Bianchi, L., Accili, E.A., and Brown, A.M. Functional consequences of ROMK mutants linked to antenatal bartters syndrome and implications for treatment. Hum. Mol. Genet., 7(6):975-980, 1998.
Kramer, J.W., Post, M.D., Brown, A.M., and Kirsch, G.E. Modulation of potassium channel gating by co-expression of KV2.1 with regulatory Kv5.1 or Kv6.1 " subunits. Amer. J. Physiol: Cell Physiol., 274:C1501-C1510, 1998.
Wible, B.A., Yang, Q., Kuryshev, Y.A., Accili, E.A., and Brown, A.M. Cloning and expression of a novel K+ channel regulatory protein, KchAP. J. Biol. Chem. 273:11745-11751, 1998.
Ficker, E., Jarolimek, W., Kiehn, J., Baumann, A. and Brown, A.M. Molecular determinants of dofetilide block of HERG K+ channels. Circ. Res. 82:386-395, 1998.
DHHS DK-97-001, "CWRU OBrien Rental Research Center," 09/01/98-08/31/03. Total: $701,020.
DHHS KL-61642, "Iron-Induced Congestive Heart Failure: New Experimental Model," 09/30/98-09/29/03. Total: $1,420,000.
DHHS HL-55404, "Inward Rectifier K+ channels," 03/08/96-01/31/01. Total: $1,503,707.
DHHS HL-36930, "Membrane Currents in Cardiac Muscle," 08/25/95-07/31/00. Total: $1,125,838.
54 post-doctoral trainees; 250 articles published in journals; 65 book chapters, several patents.